Planta Med 2019; 85(18): 1430-1431
DOI: 10.1055/s-0039-3399746
Pre-Congress Posters
Animal Healthcare and Veterinary Phytotherapy
© Georg Thieme Verlag KG Stuttgart · New York

Polyphenolics from Romanian native medicinal plants and used in veterinary medicine

E Varga
1   Department of Pharmacognosy and Phytotherapy, University of Medicine, Pharmacy, Sciences and Technology of Tîrgu Mureș, Faculty of Pharmacy,, Gheorghe Marinescu 38, 540139 Tîrgu Mureș, Romania
,
I Fülöp
2   Department of Toxicology and Biopharmacy, University of Medicine, Pharmacy, Sciences and Technology of Tîrgu Mureș, Faculty of Pharmacy,, Gheorghe Marinescu 38, 540139 Tîrgu Mureș, Romania
,
L Farczádi
3   Center for Advanced Medical and Pharmaceutical Research, Laboratory of Chromatography LC/MS, University of Medicine, Pharmacy, Sciences and Technology of Tîrgu Mureș, Faculty of Pharmacy,, Gheorghe Marinescu 38, 540139 Tîrgu Mureș, Romania
,
M Fazakas
4   SC Promedivet SRL,, Strada Lungă 46, Sovata 545503, Sovata, Romania
,
MD Croitoru
2   Department of Toxicology and Biopharmacy, University of Medicine, Pharmacy, Sciences and Technology of Tîrgu Mureș, Faculty of Pharmacy,, Gheorghe Marinescu 38, 540139 Tîrgu Mureș, Romania
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Publikationsdatum:
20. Dezember 2019 (online)

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Flavonoids and polyphenols are widely distributed in medicinal plants and have positive health effects. The aim of this study were to determine the flavonoids and polyphenols with a spectrophotometrical and by an UHPLC-LC-MS/MS method [1].

Eighteen widely used medicinal plants were studied. Total flavonoids and total polyphenolics content were determined quantitatively by spectrophotometrical method from the methanolic and ethanolic (70⁰) extracts of plants. Additionally an UHPLC-LC-MS/MS method was developed for determination of seven standards from extracts. Detection was carried out in SRM mode (chlorogenic acid, caffeic acid, quercitrin, luteolin, quercetin, apigenin, kaempferol)l.

Medicinal plants are a rich source of flavonoids and polyphenolics. The seven standard were detectabled in high concentration from Hyperici herba, Betulae folium and Potentillae herba [Fig.1.].

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Fig. 1

There are a wide variety of phenolics and flavonoids and the obtained antioxidant values confirms a high antioxidant capacities of extracts. For the determination of polyphenolic profile the developed UHPLC-DAD-QTOF-MS/MS method is fast and acceptable. Polyphenols may be developed in veterinary products and used for animals.

 

  • References

  • 1 Parets L, Alechaga E, Nunez O, Saurina J, Hernandez-Cassou S, Puignou L. Ultrahigh pressure liquid chromatography-atmospheric pressure photoionization-tandem mass spectromerty for the determination of polyphenolic profiles in the characterization and classification of cranberry-based pharmaceutical preparations and natural extracts. Anal Methods_UK 2016; 8 (22) 4363-4378.
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