Planta Med 2019; 85(18): 1471-1472
DOI: 10.1055/s-0039-3399854
Main Congress Poster
Poster Session 1
© Georg Thieme Verlag KG Stuttgart · New York

Antioxidant activity and phenolic composition of costmary (Chrysanthemum balsamita L.) flower

E Varga
1   Department of Pharmacognosy and Phytotherapy, University of Medicine, Pharmacy, Sciences and Technology of Tîrgu Mureș,, Gheorghe Marinescu 38, 540139 Tîrgu Mureș, Romania
,
E Domokos
2   Department of Pharmaceutical Botany, University of Medicine, Pharmacy, Sciences and Technology of Tîrgu Mureș,, Gheorghe Marinescu 38, 540139 Tîrgu Mureș, Romania
,
K Orbán
1   Department of Pharmacognosy and Phytotherapy, University of Medicine, Pharmacy, Sciences and Technology of Tîrgu Mureș,, Gheorghe Marinescu 38, 540139 Tîrgu Mureș, Romania
,
L Kursinszki
3   Department of Pharmacognosy, Semmelweis University,, Üllői út 26, H-1085 Budapest, Hungary
,
B Imre
4   Department of Plant Anatomy, Institute of Biology, Eötvös Loránd University, , Pázmány Péter sétány 1/C, H-1117 Budapest, Hungary
5   Eötvös Loránd University, Institutional Excellence Program, Natural Bioactive Compounds Group,, Pázmány Péter sétány 1/C, H-1117, Budapest, Hungary
,
G Tóth
5   Eötvös Loránd University, Institutional Excellence Program, Natural Bioactive Compounds Group,, Pázmány Péter sétány 1/C, H-1117, Budapest, Hungary
6   Department of Pharmaceutical Chemistry, Semmelweis University,, Hőgyes Endre u. 9, H-1092, Budapest, Hungary
› Author Affiliations
Further Information

Publication History

Publication Date:
20 December 2019 (online)

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Costmary, Chrysanthemum balsamita L., is a widely cultivated ornament plant. Previous studies have demonstrated that extracts of costmary show several bioactivities including antioxidant, diuretic, astringent, antiseptic, stomachic and anthelmintic [1]. Nevertheless, its phytochemical exploration is still incomplete. Our aim was to characterize the scavenger activity of herb methanolic extracts using in vitro ABTS method as well as identify the potential bioactive compounds by LC-ESI-QqQ and LC-ESI-high-resolution Orbitrap MS/MS methods. Based on preliminary screening notable amounts of polyphenols (64.50 ± 4.21 mg/100g) and flavonoids (21.58 ± 1.12 mg/100g) were presented in the extract. Using ABTS method an excellent antioxidant activity was measured with 1.2 ± 0.1 µg/mL IC50 value which is comparable with the scavenger activity of quercetin standard (IC50 = 3.4 ± 0.2 µg/mL). In the extract altogether 34 phenolics, comprising 14 hydroxycinnamoylquinic acids (mainly different caffeoylquinic acid derivatives) and 20 flavonoids (glycosides of apigenin, luteoilin, diosmetin, acacetin and quercetin) were identified with combination of different LC-MS techniques. Our results clearly show that costmary herb is an inexpensive, readily available natural source of phenolic compounds with a possible pharmacological and cosmetic applications.

 

  • References

  • 1 Pukalskas A, Venskutonis PR, Dijkgraaf I, van Beek TA. Isolation, identification and activity of natural antioxidants from costmary (Chrysanthemum balsamita) cultivated in Lithuania. Food Chem 2010; 122 (03) : 804-811.
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