Thromb Haemost 2019; 119(11): e1
DOI: 10.1055/s-0039-3400534
Erratum
Georg Thieme Verlag KG Stuttgart · New York

Erratum: Tie2 Activation Promotes Protection and Reconstitution of the Endothelial Glycocalyx in Human Sepsis

Carolin Christina Drost
1   Division of General Internal Medicine, Nephrology, and Rheumatology, Department of Medicine D, University Hospital Münster, Münster, Germany
,
Alexandros Rovas
1   Division of General Internal Medicine, Nephrology, and Rheumatology, Department of Medicine D, University Hospital Münster, Münster, Germany
,
Kristina Kusche-Vihrog
2   Institute of Physiology II, University Hospital Münster, Münster, Germany
,
Paul Van Slyke
3   Vasomune Therapeutics, Toronto, Ontario, Canada
,
Harold Kim
3   Vasomune Therapeutics, Toronto, Ontario, Canada
,
Van C. Hoang
3   Vasomune Therapeutics, Toronto, Ontario, Canada
,
Jason T. Maynes
4   Department of Anaesthesia and Pain Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada
,
Dirk Oliver Wennmann
1   Division of General Internal Medicine, Nephrology, and Rheumatology, Department of Medicine D, University Hospital Münster, Münster, Germany
,
Hermann Pavenstädt
1   Division of General Internal Medicine, Nephrology, and Rheumatology, Department of Medicine D, University Hospital Münster, Münster, Germany
,
Wolfgang Linke
2   Institute of Physiology II, University Hospital Münster, Münster, Germany
,
Alexander Lukasz
1   Division of General Internal Medicine, Nephrology, and Rheumatology, Department of Medicine D, University Hospital Münster, Münster, Germany
,
Bettina Hesse
1   Division of General Internal Medicine, Nephrology, and Rheumatology, Department of Medicine D, University Hospital Münster, Münster, Germany
,
Philipp Kümpers
1   Division of General Internal Medicine, Nephrology, and Rheumatology, Department of Medicine D, University Hospital Münster, Münster, Germany
› Author Affiliations
Further Information

Publication History

Publication Date:
29 January 2020 (online)

The authors have brought to the publisher's attention that there were some errors in [Fig. 1] published in the above article in Thrombosis and Haemostasis, Volume 119, Number 11, 2019 (DOI: 10.1055/s-0039-1695768). The corrected figure appears as follows:

Zoom Image
Fig. 1 Glycocalyx damage in human sepsis can be reproduced in vitro. (A) Scatter dot plot showing perfused boundary region (PBR) values from 38 septic patients and 10 nonseptic subjects, obtained via real-time intravital microscopy of the sublingual microvasculature. Data are presented as absolute values with median ± interquartile range (IQR). ★p < 0.0001 using two-tailed Mann–Whitney U test. (B) In vitro analysis of the endothelial glycocalyx (eGC) by atomic force microscopy (AFM). A subpopulation from (A) was randomly selected and endothelial cells (ECs) were incubated with 5% sterile-filtered human serum from 4 patients and 3 nonseptic subjects, respectively. Each dot represents the mean of three independent experiments (consisting of ≥ 4 indentation curves in each of ≥ 8 cells) for each individual serum. Incubation without human serum served as control. Data are presented with median ± IQR. ★p < 0.05 versus control using nonparametric analysis of variance (ANOVA) with Dunn's test. (C) Scatter plot showing the association between AFM-derived eGC (in vitro) decline and corresponding PBR values (in vivo) for the individuals from (B).