CC BY-NC-ND 4.0 · Journal of Digestive Endoscopy 2019; 10(03): 158-162
DOI: 10.1055/s-0039-3401454
Original Article
Society of Gastrointestinal Endoscopy of India

Clinical Spectrum of Chronic Lower Gastrointestinal Bleeding in Sub-Himalayas: A Study at a Tertiary Care Hospital of North India

Vikas Lakhanpal
1   Department of Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
,
Rajesh Sharma
2   Department of Gastroenterology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
,
Vishal Bodh
2   Department of Gastroenterology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
,
Surinder Thakur
1   Department of Medicine, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
,
Neetu Sharma
3   Department of Physiology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
,
Brij Sharma
2   Department of Gastroenterology, Indira Gandhi Medical College, Shimla, Himachal Pradesh, India
› Author Affiliations
Further Information

Publication History

Publication Date:
12 December 2019 (online)

Abstract

Background Lower gastrointestinal bleeding (LGIB) is fairly a common presentation in gastroenterology and medicine departments, and presents major diagnostic and therapeutic challenges. This study aimed to explore the varied clinical spectrum of LGIB in our region.

Methods A total of 138 patients presented with chronic LGIB and were investigated using colonoscopy and relevant investigations.

Results The majority of patients were in the age group of 40 to 59 years, with a mean age of 49.5 years, slight male predominance, and male-to-female ratio of 1.19:1. The most common clinical presentation was hematochezia (97.8%). Overall, 15% patients had more than one comorbidity, and 39.13% patients were anemic, of which 7.24% received blood transfusions. Diagnostic yield of colonoscopy was 92.75%.

Major causes of LGIB were anorectal causes (19.56%), inflammatory bowel disease (19.56%), colorectal carcinoma (17.39%), radiation proctitis (9.42%), infective causes (11.59%), nonspecific colitis (7.24%), and benign growths (5.07%). However, in the elderly (age > 60 years), carcinoma colon, radiation proctitis, and hemorrhoids predominated the clinical picture.

Conclusion Colonoscopy is very useful in the evaluation of patients with LGIB. The predominant causes of LGIB vary according to age as well as geographical location, and mortality of LGIB is negligible as compared with upper gastrointestinal bleeding.

 
  • References

  • 1 Strate LL. Lower GI bleeding: epidemiology and diagnosis. Gastroenterol Clin North Am 2005; 34 (04) 643-664
  • 2 Longstreth GF. Epidemiology and outcome of patients hospitalized with acute lower gastrointestinal hemorrhage: a population-based study. Am J Gastroenterol 1997; 92 (03) 419-424
  • 3 Peura DA, Lanza FL, Gostout CJ, Foutch PG. The American College of Gastroenterology Bleeding Registry: preliminary findings. Am J Gastroenterol 1997; 92 (06) 924-928
  • 4 Bloomfeld RS, Rockey DC, Shetzline MA. Endoscopic therapy of acute diverticular hemorrhage. Am J Gastroenterol 2001; 96 (08) 2367-2372
  • 5 Farrell JJ, Friedman LS. Review article: the management of lower gastrointestinal bleeding. Aliment Pharmacol Ther 2005; 21 (11) 1281-1298
  • 6 Longstreth GF. Epidemiology of hospitalization for acute upper gastrointestinal hemorrhage: a population-based study. Am J Gastroenterol 1995; 90 (02) 206-210
  • 7 Velayos FS, Williamson A, Sousa KH. et al. Early predictors of severe lower gastrointestinal bleeding and adverse outcomes: a prospective study. Clin Gastroenterol Hepatol 2004; 2 (06) 485-490
  • 8 Al Qahtani AR, Satin R, Stern J, Gordon PH. Investigative modalities for massive lower gastrointestinal bleeding. World J Surg 2002; 26 (05) 620-625
  • 9 Bhasin DK, Rana SS. Lower Gastrointestinal Bleed. Med Update 2011; 332-335
  • 10 Schmulewitz N, Fisher DA, Rockey DC. Early colonoscopy for acute lower GI bleeding predicts shorter hospital stay: a retrospective study of experience in a single center. Gastrointest Endosc 2003; 58 (06) 841-846
  • 11 Jensen DM, Machicado GA. Diagnosis and treatment of severe hematochezia. The role of urgent colonoscopy after purge. Gastroenterology 1988; 95 (06) 1569-1574
  • 12 Boley SJ, DiBiase A, Brandt LJ, Sammartano RJ. Lower intestinal bleeding in the elderly. Am J Surg 1979; 137 (01) 57-64
  • 13 Dar IA, Dar WR, Kasana BA. et al. Etiology, clinical presentation, diagnosis and management of lower gastrointestinal bleed in a tertiary care hospital in India: a retroprospective study. J Dig Endosc 2015; 6: 101-109
  • 14 Goenka MK, Kochhar R, Mehta SK. Spectrum of lower gastrointestinal hemorrhage: an endoscopic study of 166 patients. Indian J Gastroenterol 1993; 12 (04) 129-131
  • 15 Khandelwal C. Lower gastrointestinal bleeding. Indian J Surg 2003; 65: 151-155
  • 16 Bai Y, Peng J, Gao J, Zou DW, Li ZS. Epidemiology of lower gastrointestinal bleeding in China: single-center series and systematic analysis of Chinese literature with 53,951 patients. J Gastroenterol Hepatol 2011; 26 (04) 678-682
  • 17 Bokhari M, Vernava AM, Ure T, Longo WE. Diverticular hemorrhage in the elderly–is it well tolerated?. Dis Colon Rectum 1996; 39 (02) 191-195
  • 18 Strate LL, Orav EJ, Syngal S. Early predictors of severity in acute lower intestinal tract bleeding. Arch Intern Med 2003; 163 (07) 838-843