CC BY 4.0 · Aorta (Stamford) 2019; 07(06): 155-162
DOI: 10.1055/s-0039-3401810
State-of-the-Art Review
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Repair of Acute Type-A Aortic Dissection in the Present Era: Outcomes and Controversies

Ellie Moeller
1   Department of Cardiothoracic Surgery, JFK Medical Center, Atlantis, FL
,
Marcos Nores
1   Department of Cardiothoracic Surgery, JFK Medical Center, Atlantis, FL
,
1   Department of Cardiothoracic Surgery, JFK Medical Center, Atlantis, FL
› Institutsangaben
Funding This research was supported (in whole or in part) by HCA Healthcare and/or an HCA Healthcare affiliated entity. The views expressed in this publication represent those of the author(s) and do not necessarily represent the official views of HCA Healthcare or any of its affiliated entities.
Weitere Informationen

Publikationsverlauf

05. November 2018

22. Oktober 2019

Publikationsdatum:
09. April 2020 (online)

Abstract

Acute Type-A aortic dissection (AAAD) remains a surgical emergency with a relatively high operative mortality despite advances in medical and surgical management over the past three decades. In spite of the severity of disease, there is a paucity of studies reviewing key controversies surrounding AAAD repair and management. A systematic literature search was performed using Cochrane review and PubMed bibliography review. Abstracts were first reviewed for general pertinence and then articles were reviewed in full. Literature review indicates that use of moderate hypothermia and antegrade cerebral perfusion is a safe alternative to deep hypothermia. In hemodynamically stable patients, axillary cannulation may be substituted for femoral cannulation. With regard to the technical aspects of repair, preserving the aortic root whenever possible and performing the distal anastomosis with the open distal technique rather than with the clamp on is the preferred approach. In patients with a patent false lumen, close monitoring is indicated. As demonstrated by the literature, significant improvement of early and late mortality over the past years has occurred in patients presenting with AAAD. Repair of acute Type-A aortic dissection remains a challenge with high operative mortality; however, improvement of surgical techniques and management have resulted in improvement of early and late clinical outcomes.

 
  • References

  • 1 Conway BD, Stamou SC, Kouchoukos NT, Lobdell KW, Hagberg RC. Effects of gender on outcomes and survival following repair of acute type A aortic dissection. Int J Angiol 2015; 24 (02) 93-98
  • 2 Tolis Jr G, Sundt III TM. Contemporary insights into the management of type A aortic dissection. Expert Rev Cardiovasc Ther 2016; 14 (10) 1189-1196
  • 3 Skripochnik E, Friedman P, Michler RE, Neragi-Miandoab S. The outcome of surgical management of type A aortic dissection. Asian Cardiovasc Thorac Ann 2014; 22 (06) 687-693
  • 4 Pape LA, Awais M, Woznicki EM. , et al. Presentation, diagnosis, and outcomes of acute aortic dissection: 17-year trends from the International Registry of Acute Aortic Dissection. J Am Coll Cardiol 2015; 66 (04) 350-358
  • 5 Algarni KD, Yanagawa B, Rao V, Yau TM. Profound hypothermia compared with moderate hypothermia in repair of acute type A aortic dissection. J Thorac Cardiovasc Surg 2014; 148 (06) 2888-2894
  • 6 Griepp RB, Stinson EB, Hollingsworth JF, Buehler D. Prosthetic replacement of the aortic arch. J Thorac Cardiovasc Surg 1975; 70 (06) 1051-1063
  • 7 Gega A, Rizzo JA, Johnson MH, Tranquilli M, Farkas EA, Elefteriades JA. Straight deep hypothermic arrest: experience in 394 patients supports its effectiveness as a sole means of brain preservation. Ann Thorac Surg 2007; 84 (03) 759-766 , discussion 766–767
  • 8 Percy A, Widman S, Rizzo JA, Tranquilli M, Elefteriades JA. Deep hypothermic circulatory arrest in patients with high cognitive needs: full preservation of cognitive abilities. Ann Thorac Surg 2009; 87 (01) 117-123
  • 9 Numata S, Tsutsumi Y, Monta O. , et al. Acute type A aortic dissection repair with mild-to-moderate hypothermic circulatory arrest and selective cerebral perfusion. J Cardiovasc Surg (Torino) 2015; 56 (04) 525-530
  • 10 Stamou SC, Rausch LA, Kouchoukos NT. , et al. Comparison between antegrade and retrograde cerebral perfusion or profound hypothermia as brain protection strategies during repair of type A aortic dissection. Ann Cardiothorac Surg 2016; 5 (04) 328-335
  • 11 Ueda Y. What is the best method for brain protection in surgery of the aortic arch? Retrograde cerebral perfusion. Cardiol Clin 2010; 28 (02) 371-379
  • 12 Bakhtiary F, Dogan S, Zierer A. , et al. Antegrade cerebral perfusion for acute type A aortic dissection in 120 consecutive patients. Ann Thorac Surg 2008; 85 (02) 465-469
  • 13 Stamou SC, McHugh MA, Conway BD, Nores M. Role of moderate hypothermia and antegrade cerebral perfusion during repair of type a aortic dissection. Int J Angiol 2018; 27 (04) 190-195
  • 14 McKhann GM, Goldsborough MA, Borowicz Jr LM. , et al. Predictors of stroke risk in coronary artery bypass patients. Ann Thorac Surg 1997; 63 (02) 516-521
  • 15 Halkos ME, Kerendi F, Myung R, Kilgo P, Puskas JD, Chen EP. Selective antegrade cerebral perfusion via right axillary artery cannulation reduces morbidity and mortality after proximal aortic surgery. J Thorac Cardiovasc Surg 2009; 138 (05) 1081-1089
  • 16 Doenst T, Wijeysundera D, Karkouti K. , et al. Hyperglycemia during cardiopulmonary bypass is an independent risk factor for mortality in patients undergoing cardiac surgery. J Thorac Cardiovasc Surg 2005; 130 (04) 1144
  • 17 Karkouti K, Djaiani G, Borger MA. , et al. Low hematocrit during cardiopulmonary bypass is associated with increased risk of perioperative stroke in cardiac surgery. Ann Thorac Surg 2005; 80 (04) 1381-1387
  • 18 Ren Z, Wang Z, Hu R. , et al. Which cannulation (axillary cannulation or femoral cannulation) is better for acute type A aortic dissection repair? A meta-analysis of nine clinical studies. Eur J Cardiothorac Surg 2015; 47 (03) 408-415
  • 19 Tiwari KK, Murzi M, Bevilacqua S, Glauber M. Which cannulation (ascending aortic cannulation or peripheral arterial cannulation) is better for acute type A aortic dissection surgery?. Interact Cardiovasc Thorac Surg 2010; 10 (05) 797-802
  • 20 Stamou SC, Gartner D, Kouchoukos NT. , et al. Axillary versus femoral arterial cannulation during repair of type A aortic dissection?: an old problem seeking new solutions. Aorta (Stamford) 2016; 4 (04) 115-123
  • 21 Neri E, Massetti M, Capannini G. , et al. Axillary artery cannulation in type a aortic dissection operations. J Thorac Cardiovasc Surg 1999; 118 (02) 324-329
  • 22 Kokotsakit J, Lazopoulos G, Milonakis M. , et al. Right axillary artery cannulation for surgical management of the hostile ascending aorta. Tex Heart Inst J 2005; 32 (02) 189-193 , discussion 185
  • 23 Benedetto U, Raja SG, Amrani M. , et al. The impact of arterial cannulation strategy on operative outcomes in aortic surgery: evidence from a comprehensive meta-analysis of comparative studies on 4476 patients. J Thorac Cardiovasc Surg 2014; 148 (06) 2936-43.e1 , 4
  • 24 Gulbins H, Pritisanac A, Ennker J. Axillary versus femoral cannulation for aortic surgery: enough evidence for a general recommendation?. Ann Thorac Surg 2007; 83 (03) 1219-1224
  • 25 Klotz S, Heuermann K, Hanke T, Petersen M, Sievers HH. Outcome with peripheral versus central cannulation in acute type A dissection. Interact Cardiovasc Thorac Surg 2015; 20 (06) 749-753 , discussion 754
  • 26 Abe T, Usui A. The cannulation strategy in surgery for acute type A dissection. Gen Thorac Cardiovasc Surg 2017; 65 (01) 1-9
  • 27 Moizumi Y, Motoyoshi N, Sakuma K, Yoshida S. Axillary artery cannulation improves operative results for acute type a aortic dissection. Ann Thorac Surg 2005; 80 (01) 77-83
  • 28 Reuthebuch O, Schurr U, Hellermann J. , et al. Advantages of subclavian artery perfusion for repair of acute type A dissection. Eur J Cardiothorac Surg 2004; 26 (03) 592-598
  • 29 Orihashi K. Malperfusion in acute type a aortic dissection: unsolved problem. Ann Thorac Surg 2013; 95 (05) 1570-1576
  • 30 Pasic M, Schubel J, Bauer M. , et al. Cannulation of the right axillary artery for surgery of acute type A aortic dissection. Eur J Cardiothorac Surg 2003; 24 (02) 231-235 , discussion 235–236
  • 31 Etz CD, Plestis KA, Kari FA. , et al. Axillary cannulation significantly improves survival and neurologic outcome after atherosclerotic aneurysm repair of the aortic root and ascending aorta. Ann Thorac Surg 2008; 86 (02) 441-446 , discussion 446–447
  • 32 Lee HK, Kim GJ, Cho JY, Lee JT, Park I, Lee YO. Comparison of the outcomes between axillary and femoral artery cannulation for acute type A aortic dissection. Korean J Thorac Cardiovasc Surg 2012; 45 (02) 85-90
  • 33 Sadi L, Tønnessen T, Pillgram-Larsen J. Short and long-term survival in type A aortic dissection justifies the operative risk and effort. Scand Cardiovasc J 2012; 46 (01) 45-50
  • 34 Etz CD, von Aspern K, da Rocha E Silva J. , et al. Impact of perfusion strategy on outcome after repair for acute type a aortic dissection. Ann Thorac Surg 2014; 97 (01) 78-85
  • 35 Khaladj N, Shrestha M, Peterss S. , et al. Ascending aortic cannulation in acute aortic dissection type A: the Hannover experience. Eur J Cardiothorac Surg 2008; 34 (04) 792-796 , 796
  • 36 Krüger T, Conzelmann LO, Bonser RS. , et al. Acute aortic dissection type A. Br J Surg 2012; 99 (10) 1331-1344
  • 37 Gunn TM, Stamou SC, Kouchoukos NT. Techniques of Proximal Root Reconstruction and Outcomes Following Repair of Acute Type A Aortic Dissection. Aorta (Stamford) 2016; 4 (02) 33-41
  • 38 Pochettino A, Brinkman WT, Moeller P. , et al. Antegrade thoracic stent grafting during repair of acute DeBakey I dissection prevents development of thoracoabdominal aortic aneurysms. Ann Thorac Surg 2009; 88 (02) 482-489 , discussion 489–490
  • 39 Danner BC, Natour E, Horst M, Dikov V, Ghosh PK, Dapunt OE. Comparison of operative techniques in acute type A aortic dissection performing the distal anastomosis. J Card Surg 2007; 22 (02) 105-110
  • 40 Lai DT, Miller DC, Mitchell RS. , et al. Acute type A aortic dissection complicated by aortic regurgitation: composite valve graft versus separate valve graft versus conservative valve repair. J Thorac Cardiovasc Surg 2003; 126 (06) 1978-1986
  • 41 Moon MR, Sundt III TM, Pasque MK. , et al. Does the extent of proximal or distal resection influence outcome for type A dissections?. Ann Thorac Surg 2001; 71 (04) 1244-1249 , discussion 1249–1250
  • 42 Pansini S, Gagliardotto PV, Pompei E. , et al. Early and late risk factors in surgical treatment of acute type A aortic dissection. Ann Thorac Surg 1998; 66 (03) 779-784
  • 43 Pessotto R, Santini F, Pugliese P. , et al. Preservation of the aortic valve in acute type A dissection complicated by aortic regurgitation. Ann Thorac Surg 1999; 67 (06) 2010-2013 , discussion 2014–2019
  • 44 Ehrlich MP, Ergin MA, McCullough JN. , et al. Results of immediate surgical treatment of all acute type A dissections. Circulation 2000; 102 (19) (Suppl. 03) III248-III252
  • 45 Elefteriades JA. What operation for acute type A dissection?. J Thorac Cardiovasc Surg 2002; 123 (02) 201-203
  • 46 Stamou SC, Kouchoukos NT, Hagberg RC. , et al. Does the technique of distal anastomosis influence clinical outcomes in acute type A aortic dissection?. Interact Cardiovasc Thorac Surg 2011; 12 (03) 404-408
  • 47 Trimarchi S, Nienaber CA, Rampoldi V. , et al; International Registry of Acute Aortic Dissection Investigators. Contemporary results of surgery in acute type A aortic dissection: The International Registry of Acute Aortic Dissection experience. J Thorac Cardiovasc Surg 2005; 129 (01) 112-122
  • 48 Conway BD, Stamou SC, Kouchoukos NT. , et al. Effects of hemodynamic instability on early outcomes and late survival following repair of acute type A aortic dissection. Aorta (Stamford) 2014; 2 (01) 22-27
  • 49 Kawahito K, Adachi H, Murata S, Yamaguchi A, Ino T. Coronary malperfusion due to type A aortic dissection: mechanism and surgical management. Ann Thorac Surg 2003; 76 (05) 1471-1476 , discussion 1476
  • 50 Neri E, Toscano T, Papalia U. , et al. Proximal aortic dissection with coronary malperfusion: presentation, management, and outcome. J Thorac Cardiovasc Surg 2001; 121 (03) 552-560
  • 51 Geirsson A, Szeto WY, Pochettino A. , et al. Significance of malperfusion syndromes prior to contemporary surgical repair for acute type A dissection: outcomes and need for additional revascularizations. Eur J Cardiothorac Surg 2007; 32 (02) 255-262
  • 52 Vallabhajosyula P, Gottret JP, Bavaria JE, Desai ND, Szeto WY. Endovascular repair of the ascending aorta in patients at high risk for open repair. J Thorac Cardiovasc Surg 2015; 149 (2, Suppl) S144-S150
  • 53 Kolvenbach RR, Karmeli R, Pinter LS. , et al. Endovascular management of ascending aortic pathology. J Vasc Surg 2011; 53 (05) 1431-1437
  • 54 Pires de Morais G, Rodrigues A, Gama V. Treatment of type-A aortic dissection using endoprosthesis occurring after coronary artery bypass surgery. Catheter Cardiovasc Interv 2012; 80 (07) 1099-1104
  • 55 Ronchey S, Serrao E, Alberti V. , et al. Endovascular stenting of the ascending aorta for type A aortic dissections in patients at high risk for open surgery. Eur J Vasc Endovasc Surg 2013; 45 (05) 475-480
  • 56 Spear R, Kaladji A, Roeder B, Haulon S. Endovascular repair of a chronic arch dissecting aneurysm with a branched endograft. Ann Thorac Surg 2013; 96 (02) e39-e41
  • 57 Bernard Y, Zimmermann H, Chocron S. , et al. False lumen patency as a predictor of late outcome in aortic dissection. Am J Cardiol 2001; 87 (12) 1378-1382
  • 58 Yu HY, Chen YS, Huang SC, Wang SS, Lin FY. Late outcome of patients with aortic dissection: study of a national database. Eur J Cardiothorac Surg 2004; 25 (05) 683-690
  • 59 Fattouch K, Sampognaro R, Navarra E. , et al. Long-term results after repair of type a acute aortic dissection according to false lumen patency. Ann Thorac Surg 2009; 88 (04) 1244-1250
  • 60 Larsen M, Bartnes K, Tsai TT. , et al. Extent of preoperative false lumen thrombosis does not influence long-term survival in patients with acute type A aortic dissection. J Am Heart Assoc 2013; 2 (04) e000112
  • 61 Kimura N, Tanaka M, Kawahito K, Yamaguchi A, Ino T, Adachi H. Influence of patent false lumen on long-term outcome after surgery for acute type A aortic dissection. J Thorac Cardiovasc Surg 2008; 136 (05) 1160-1166 , 1166.e1–1166.e3
  • 62 Park KH, Lim C, Choi JH. , et al. Midterm change of descending aortic false lumen after repair of acute type I dissection. Ann Thorac Surg 2009; 87 (01) 103-108
  • 63 Bing F, Rodière M, Martinelli T. , et al. Type A acute aortic dissection: why does the false channel remain patent after surgery?. Vasc Endovascular Surg 2014; 48 (03) 239-245
  • 64 Hagan PG, Nienaber CA, Isselbacher EM. , et al. The International Registry of Acute Aortic Dissection (IRAD): new insights into an old disease. JAMA 2000; 283 (07) 897-903
  • 65 JCS Joint Working Group. Guidelines for diagnosis and treatment of aortic aneurysm and aortic dissection (JCS 2011): digest version. Circ J 2013; 77 (03) 789-828
  • 66 Erbel R, Aboyans V, Boileau C. , et al; ESC Committee for Practice Guidelines; The Task Force for the Diagnosis and Treatment of Aortic Diseases of the European Society of Cardiology (ESC). 2014 ESC Guidelines on the diagnosis and treatment of aortic diseases: document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. Eur Heart J 2014; 35 (41) 2873-2926
  • 67 Tanaka A, Ishii H, Suzuki S. , et al. Influence of false lumen status on the prognosis of acute type a aortic dissection without urgent surgical treatment. J Atheroscler Thromb 2017; 24 (02) 169-175
  • 68 Kitai T, Kaji S, Yamamuro A. , et al. Clinical outcomes of medical therapy and timely operation in initially diagnosed type a aortic intramural hematoma: a 20-year experience. Circulation 2009; 120 (11, Suppl): S292-S298
  • 69 Song JK, Yim JH, Ahn JM. , et al. Outcomes of patients with acute type a aortic intramural hematoma. Circulation 2009; 120 (21) 2046-2052
  • 70 Kitamura T, Torii S, Horai T. , et al. Outcomes of patients who declined surgery for acute Stanford type A aortic dissection with patent false lumen of the ascending aorta. Interact Cardiovasc Thorac Surg 2017; 25 (01) 47-51
  • 71 Ando T, Kobayashi T, Endo H. , et al. Surgical treatment or conservative therapy for stanford type a acute aortic dissection with a thrombosed false lumen. Ann Vasc Dis 2012; 5 (04) 428-434
  • 72 Kurimoto Y, Morishita K, Kawaharada N, Fukada J, Asai Y, Abe T. Initial management of acute type-A aortic dissection with a thrombosed false lumen: a retrospective cohort study. Surg Today 2004; 34 (08) 652-657
  • 73 Zierer A, Voeller RK, Hill KE, Kouchoukos NT, Damiano Jr RJ, Moon MR. Aortic enlargement and late reoperation after repair of acute type A aortic dissection. Ann Thorac Surg 2007; 84 (02) 479-486 , discussion 486–487
  • 74 Rylski B, Milewski RK, Bavaria JE. , et al. Outcomes of surgery for chronic type A aortic dissection. Ann Thorac Surg 2015; 99 (01) 88-93
  • 75 Rylski B, Beyersdorf F, Desai ND. , et al. Distal aortic reintervention after surgery for acute DeBakey type I or II aortic dissection: open versus endovascular repair. Eur J Cardiothorac Surg 2015; 48 (02) 258-263
  • 76 Fann JI, Smith JA, Miller DC. , et al. Surgical management of aortic dissection during a 30-year period. Circulation 1995; 92 (9, Suppl): II113-II121
  • 77 Conway BD, Stamou SC, Kouchoukos NT. , et al. Improved clinical outcomes and survival following repair of acute type A aortic dissection in the current era. Interact Cardiovasc Thorac Surg 2014; 19 (06) 971-976