Klin Padiatr 2020; 232(02): 110
DOI: 10.1055/s-0040-1701936
16 May 2020
S-IX
Session IX: Staging Evaluation and Response Criteria Harmonization (SEARCH) for CAYAHL
© Georg Thieme Verlag KG Stuttgart · New York

The impact of the Point-spread-function (PSF) reconstruction on the response assessment in the Interim-PET (iPET) in Hodgkin lymphoma (HL)

TW Georgi
1   Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany
,
L Kurch
1   Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany
,
D Hasenclever
2   Statistics and Epidemiology, University of Leipzig, Institute for Medical Informatics, Leipzig, Germany
,
D Körholz
3   Department of Pediatric Oncology, Justus-Liebig-University Gießen, Gießen, Germany
,
O Sabri
1   Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany
,
R Kluge
1   Department of Nuclear Medicine, University of Leipzig, Leipzig, Germany
,
C Mauz-Körholz
3   Department of Pediatric Oncology, Justus-Liebig-University Gießen, Gießen, Germany
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Publikationsdatum:
18. März 2020 (online)

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Introduction Within the EuroNet-PHL-C2 study the iPET result has an impact on the further treatment. The iPET assessment is done quantitatively by the qPET method (mean SUV of the hottest connected voxel inside the tumor divided by mean SUV of the liver). A qPET-value < 1.30 corresponds to a Deauville score ≤ 3 and implies omission of radiotherapy (RTx). The aim of this study was to investigate the impact of the PSF reconstruction on the further treatment decision in comparison to a pure Ordered-subset-expectation-maximization reconstruction without PSF (OSEM) (current standard).