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DOI: 10.1055/s-0040-1704106
INTRADUCTAL TUBULOPAPILLARY NEOPLASM (ITPN) AN UNUSUAL PANCREATIC LESION - A CASE REPORT
Publikationsverlauf
Publikationsdatum:
23. April 2020 (online)
A 61-year-old woman was referred for mild biliary and pancreatic duct ectasia on MRI.
EUS revealed a 12 mm, isoechoic, intraductal pancreatic head lesion. ERCP-pancreatoscopy showed a polypoid lesión suggesting intraductal papillary mucinous neoplasm (IPMN).
Final histopathology of surgical specimen (duodenopancreatectomy) revealed an uncommon entity: Intraductal tubulopapillary neoplasm (ITPN).
ITPN is a subtype of premalignant pancreatic neoplasms, distinct from IPMN. ITPN show tubulopapillary growth, cuboidal to columnar and scarce mucin. Immunohistochemical studies may also be distinctive.
ITPN has a more favorable prognosis. The role of EUS and pancreatoscopy has to be determined but might potentially help in preoperative diagnosis.