Endoscopy 2020; 52(S 01): S40
DOI: 10.1055/s-0040-1704124
ESGE Days 2020 oral presentations
Thursday, April 23, 2020 08:30 – 10:00 Take a pill Wicklow Meeting Room 3
© Georg Thieme Verlag KG Stuttgart · New York

PREVALENCE OF GASTROINTESTINAL DISEASE IN AN ASYMPTOMATIC POPULATION USING VIDEOCAPSULE

FER Vuik
1   Erasmus MC University Medical Center, Department of Gastroenterology and Hepatology, Rotterdam, Netherlands
,
SAV Nieuwenburg
1   Erasmus MC University Medical Center, Department of Gastroenterology and Hepatology, Rotterdam, Netherlands
,
S Moen
1   Erasmus MC University Medical Center, Department of Gastroenterology and Hepatology, Rotterdam, Netherlands
,
EH Schreuders
1   Erasmus MC University Medical Center, Department of Gastroenterology and Hepatology, Rotterdam, Netherlands
,
C Spada
2   Poliambulanza Foundation, Digestive Endoscopy and Gastroenterology Unit, Bresca, Italy
3   Catholic University College of Medicine, Digestive Endoscopy Unit, Fondazione Policlinico Universitario Agostino Gemelli - IRCCS, Rome, Italy
,
O Epstein
4   Royal Free Hospital, Centre for Gastroenterology, London, UK
,
I Fernández-Urién
5   Complejo Hospitalario de Navarra, Department of Gastroenterology and Hepatology, Pamplona, Spain
,
I Lansdorp-Vogelaar
6   Erasmus MC University Medical Center, Department of Public Health, Rotterdam, Netherlands
,
EJ Kuipers
1   Erasmus MC University Medical Center, Department of Gastroenterology and Hepatology, Rotterdam, Netherlands
,
MCW Spaander
1   Erasmus MC University Medical Center, Department of Gastroenterology and Hepatology, Rotterdam, Netherlands
› Author Affiliations
Further Information

Publication History

Publication Date:
23 April 2020 (online)

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Aims Although gastrointestinal (GI) diseases are common, prevalence rates of lesions in the GI tract in an asymptomatic population are difficult to assess. Colon capsule endoscopy (CCE) is a safe, minimally invasive tool that images the entire GI tract. The aim of this study is to assess prevalence of lesions in the entire GI tract in an asymptomatic population by CCE.

Methods Between 2017-2019, healthy subjects participating in the Rotterdam longitudinal epidemiological study (aged 50-75 years) were invited to receive CCE with corresponding bowel preparation. Trained reviewers analyzed images of the esophagus, stomach, small bowel and colon. Abnormalities defined as significant: Barret segment > 3 cm, severe ulceration, small bowel villous atrophy, vascular abnormalities, polyp > 10mm or ≥ 3 polyps in small bowel or colon, and cancer. Endoscopies were performed if significant lesions were found.

Results Of the 2800 invited asymptomatic subjects, 462 (16.5%) agreed to participate (mean age 66.8 years, male 46.1%). 451 procedures were analyzed. In 94.4% the capsule reached the descending colon and excretion was observed in 51.2%. In 76.6% the colon cleansing score was deemed adequate. Esophageal abnormalities were found in 14.5%, with Barret esophagus (8.3%) and esophagitis (5.5%) most common. Gastric abnormalities were reported in 28.1%, most frequently, fundic glands (18.1%) and erosions (6.6%). Small bowel abnormalities were found in 64.6%, with lymphangiectasia (30.7%) most frequent. Colon abnormalities were present in 93.3%, most commonly diverticula (81.5%) and polyps (55.9%). Significant abnormalities were found in 12%.

Conclusions In an asymptomatic population, GI tract mucosal abnormalities are frequently observed, mainly in the small bowel and colon. In over 10% of the population significant lesions were found. This study provides a frame of reference on the prevalence of GI mucosal abnormalities in an asymptomatic population.