Endoscopy 2020; 52(S 01): S129
DOI: 10.1055/s-0040-1704396
ESGE Days 2020 oral presentations
Saturday, April 25, 2020 11:00 – 13:00 Esophageal therapy: No limits?! Wicklow Meeting Room 3
© Georg Thieme Verlag KG Stuttgart · New York

CLINICAL OUTCOMES OF PATIENTS WITH ENDOSCOPIC SUBMUCOSAL DISSECTION OF EGC WITH UNDIFFERENTIATED TYPE HISTOLOGY

JJ Park
1   Korea University College of Medicine Guro Hospital, Seoul, Korea, Republic of
,
WS Kim
1   Korea University College of Medicine Guro Hospital, Seoul, Korea, Republic of
,
SM Kim
1   Korea University College of Medicine Guro Hospital, Seoul, Korea, Republic of
,
AY Yoo
1   Korea University College of Medicine Guro Hospital, Seoul, Korea, Republic of
,
HJ Chun
2   Korea University College of Medicine Anam Hospital, Seoul, Korea, Republic of
,
SH Kim
1   Korea University College of Medicine Guro Hospital, Seoul, Korea, Republic of
,
SW Lee
3   Korea University College of Medicine Ansan Hospital, Gyeonggi-do, Korea, Republic of
,
CH Yang
4   DongGuk University Gyeongju Hospital, Gyeongju, Korea, Republic of
› Author Affiliations
Further Information

Publication History

Publication Date:
23 April 2020 (online)

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Aims Clinical efficacy of endoscopic resection of early gastric cancer (EGC) with undifferentiated type histology are still under controversy. We aimed in this study to evaluate the clinical outcomes of endoscopic submucosal dissection (ESD) of EGC with undifferentiated type histology.

Methods We enrolled patients with EGC with undifferentiated type histology who underwent endoscopic submucosal dissection (ESD) at tertiary medical center. The clinical outcomes including curative resection rates and recurrence rates were retrospectively extracted and analyzed.

Results From 2007 to 2016, 75 EGCs with undifferentiated-type histology from 75 patients were identified. Mean age was 60.6 ±11.5 years and male were 46 (61.3%). Tumor location was most frequent at antrum (35/75, 46.7%), followed by corpus (20/75, 26.7%), angle (14/75, 18.7%) and high body and cardia (6/75, 8.0%). Mean tumor size was 18.2 ±7.8mm, and 17 (22.6%) showed submucosal invasion. Curative resection was estimated in 44 patients (58.7%). Among patients with non-curative resection, 6 patients (19.4%) underwent additional ESD, 8 (25.8%) additional surgery, and 17 (54.8%) was followed-up without additional treatment. After excluding 17 patients of follow-up loss more than 12month and additional surgery, recurrence was found in 2 patients (3.4%) during 55 (1-125) months (metachronous 1, distant metastasis 1). All the patients of recurrent cases were corresponding to non-curative resection and only observation was conducted.

Conclusions Due to lower curative resection rate, ESD for EGC with undifferentiated-type histology should be cautiously selected. In case of non-curative resection, additional treatment such as re-do ESD or surgery should be considered due to risk of recurrence.