Endoscopy 2020; 52(S 01): S156
DOI: 10.1055/s-0040-1704481
ESGE Days 2020 ePoster Podium presentations
Friday, April 24, 2020 09:00 – 09:30 Enteroscopy 1 ePoster Podium 5
© Georg Thieme Verlag KG Stuttgart · New York

CLINICOPATHOLOGICAL FEATURES OF SMALL BOWEL MALIGNANCIES DIAGNOSED BY VIDEO CAPSULE ENDOSCOPY AND BALLOON-ASSISTED ENTEROSCOPY: A SINGLE CENTER EXPERIENCE

AY Yoo
1   Korea University College of Medicine Guro Hospital, Seoul, Korea, Republic of
,
SM Kim
1   Korea University College of Medicine Guro Hospital, Seoul, Korea, Republic of
,
JJ Park
1   Korea University College of Medicine Guro Hospital, Seoul, Korea, Republic of
,
WS Kim
1   Korea University College of Medicine Guro Hospital, Seoul, Korea, Republic of
,
HJ Chun
2   Korea University College of Medicine Anam Hospital, Seoul, Korea, Republic of
,
SH Kim
1   Korea University College of Medicine Guro Hospital, Seoul, Korea, Republic of
,
SW Lee
3   Korea University College of Medicine Ansan Hospital, Gyeonggi-do, Korea, Republic of
,
CH Yang
4   DongGuk University Gyeongju Hospital, Gyeongju, Korea, Republic of
,
BJ Lee
5   Korea University College of Medicine Guro Hospital, gastroenterology, Seoul, Korea, Republic of
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Publikationsdatum:
23. April 2020 (online)

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Aims Small bowel malignancies often present a diagnostic challenge due to their relative rarity and nonspecific findings. However, technical developments in endoscopic instruments, including video capsule endoscopy (VCE) and enteroscopy, allow visualization of the entire small bowel. This study aimed to investigate the clinicopathological features of small bowel malignant cancers diagnosed by VCE and double-balloon enteroscopy (DBE) in a single tertiary center.

Methods We retrospectively analyzed VCE and DBE findings from Korea University Guro Hospital from January 2010 through September 2019.

Results A total of 510 VCE and 126 DBE exams was performed in 478 patients. Small bowel malignancies were diagnosed in 29 patients (15 males; mean age, 60.1 years; range, 38 to 81 years): 8 patients had lymphoma, 8 had primary adenocarcinoma, 7 had gastrointestinal stromal tumor (GIST), 5 had metastatic cancer, and 1 had neuroendocrine tumor (NET). Abdominal pain and obstructive symptoms were the most common findings in malignant lymphoma (8/8, 100%) and metastatic cancer (4/5, 80%). On the other hand, obscure gastrointestinal bleeding was the most common symptom of GIST (6/7, 85.7%) and adenocarcinoma (3/8, 37.5%). Among the 8 cases of lymphoma, 5 were diffuse large B cell lymphoma, 2 were mucosa-associated lymphoid tissue lymphoma, and 1 was peripheral T-cell lymphoma. The most common location of lymphoma was the ileum (8/8, 100%). In contrast, most common location of GIST was the proximal small bowel, including the duodenum (5/7, 71.4%).

Conclusions Approximately 6% of the patients who received both VCE and DBE were diagnosed with small bowel malignancy. Malignant lymphoma, adenocarcinoma, and GIST were the most common malignant small bowel tumors. These findings demonstrate the different clinical characteristics among small bowel malignancies and merit further study.