Endoscopy 2020; 52(S 01): S216
DOI: 10.1055/s-0040-1704675
ESGE Days 2020 ePoster Podium presentations
Saturday, April 25, 2020 11:00 – 11:30 Upper GI: Endoscopic diagnosis 3 ePoster Podium 6
© Georg Thieme Verlag KG Stuttgart · New York

 SECOND-GENERATION MAGNETICALLY CONTROLLED CAPSULE GASTROSCOPY FOR BETTER DIAGNOSIS OF UPPER GASTROINTESTINAL TRACT: A RANDOMIZED CONTROLLED CLINICAL TRIAL

B Jiang
Naval Medical University, National Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Shanghai, China
,
Y-Y Qian
Naval Medical University, National Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Shanghai, China
,
J Pan
Naval Medical University, National Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Shanghai, China
,
X Jiang
Naval Medical University, National Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Shanghai, China
,
Y-C Wang
Naval Medical University, National Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Shanghai, China
,
J-H Zhu
Naval Medical University, National Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Shanghai, China
,
W-B Zou
Naval Medical University, National Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Shanghai, China
,
J Xia
Naval Medical University, National Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Shanghai, China
,
X Liu
Naval Medical University, National Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Shanghai, China
,
W Zhou
Naval Medical University, National Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Shanghai, China
,
Z-S Li
Naval Medical University, National Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Shanghai, China
,
Z Liao
Naval Medical University, National Clinical Research Center for Digestive Diseases, Department of Gastroenterology, Shanghai, China
› Author Affiliations
Further Information

Publication History

Publication Date:
23 April 2020 (online)

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Aims Compared to conventional endoscopy, magnetically controlled capsule gastroscopy (MCCG) can be further optimized in gastric examination time and complete visualization of upper gastrointestinal (UGI) mucosa. The second-generation MCCG (MCCG-2) was developed with higher image resolution and adaptive frame rate, and we aimed to evaluate its clinical availability for UGI examination in this study.

Methods Consecutive patients undergoing MCCG examination between May to June 2019 were prospectively enrolled and randomized to swallow the first-generation MCCG (MCCG-1) or MCCG-2 in a 1:1 ratio. The main outcomes included visualization of the esophagus and duodenum, operation related parameters, image quality, maneuverability, detection of lesions, as well as safety evaluation.

Results Eighty patients were enrolled. In MCCG-2 group, frames captured for esophageal mucosa and Z-line were 171.00 and 2.00, significantly increased from those in MCCG-1 group with 97.00 and 0.00 (P = 0.002 and 0.028). The gastric examination time was shortened from 7.78 ± 0.97 min to 5.27 ± 0.74 min (P < 0.001), with the total running time of capsule extended from 702.83 min to 1001.99 min (P < 0.001). MCCG-2 also greatly improved the image quality (P < 0.001) and maneuverability (P < 0.01). No statistical difference existed in the detection of lesions between the two groups, and no adverse events occurred.

Conclusions MCCG-2 showed better performance in mucosal visualization, examination duration and maneuverability, making better diagnosis of UGI diseases a possibility.