Endoscopy 2020; 52(S 01): S257
DOI: 10.1055/s-0040-1704805
ESGE Days 2020 ePoster presentations
Thursday, April 23, 2020 09:00 – 17:00 Clinical endoscopic practice ePoster area
© Georg Thieme Verlag KG Stuttgart · New York

LONG-TERM FOLLOW-UP OF PARKINSON´S DISEASE PATIENTS TREATED WITH PEG-J DRUG DELIVERY SYSTEM

I Boeva
1   Acibadem City Clinic Tokuda Hospital, Sofia, Bulgaria
,
P Karagyozov
1   Acibadem City Clinic Tokuda Hospital, Sofia, Bulgaria
,
I Tishkov
1   Acibadem City Clinic Tokuda Hospital, Sofia, Bulgaria
› Author Affiliations
Further Information

Publication History

Publication Date:
23 April 2020 (online)

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Aims To establish the incidence of post-procedural (early) and device-related (late) adverse events in patients treated with the PEG-J delivery system for their Parkinson’s disease.

Methods We have conducted a retrospective study of a group of 92 patients who underwent a PEG-J (Freka PEG CH15 and Freka CH9 Intestinal Tube) placement between 2014 and 2019. For all patients, the jejunal catheter was introduced under endoscopic control only. PPI and antibiotic were infused periprocedurally as prophylaxis. We defined as early complications the events that have occurred within the first 30 days after the PEG-J placement and late complications – the events after the 30th day. The patients’ long-term tolerance to the delivery device, the occurrence of complications, and the factors related to them were analyzed.

Results The mean age in the group was 67.9 years (47–83). Male patients were prevalent (72,4%). The median follow-up time was 31 months. One patient (1.1%) left the program due to recurrent pain.

The overall complication rate was 7.6% (n7). Two (2.2%) patients developed complications within the first 30 post-procedural days (one Clostridium Difficile colitis and one mesenteric thrombosis).

We observed late adverse events in 5.4% (n5) of the patients. Three of them developed decubital pyloric and duodenal ulceration, which entailed removal of the jejunal extension and further use of medication (PPI/PPI + H.p. eradication). Buried bumper syndrome was diagnosed in two patients, which required a surgical extraction (local excision and laparoscopy). The average time it took for complications to emerge was 30 months. Sixty 60% of those with late complications (3/5) were positive for H. pylori infection.

Conclusions The permanent exposure to the PEG-J system is associated with relatively low complication rate. The need of follow-up gastroscopy is questionable for these patients. We suggest conducting a H. pylori examination and eradication before the PEG-J placement.