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Synlett 2021; 32(05): 502-504
DOI: 10.1055/s-0040-1707243
DOI: 10.1055/s-0040-1707243
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The Power of Transition Metals: An Unending Well-Spring of New Reactivity
Carbonylative Suzuki–Miyaura Coupling Reactions of Aryl Iodides with Readily Available Polymer-Immobilized Palladium Nanoparticles
This work was supported in part by a Grant-in-Aid for Scientific Research from JSPS, the University of Tokyo, and MEXT (Japan), JST.Further Information
Publication History
Received: 27 May 2020
Accepted after revision: 10 July 2020
Publication Date:
26 August 2020 (online)
Dedicated to Professor Barry M. Trost to celebrate his great contributions to organic synthesis
Abstract
Polysilane/alumina-supported palladium nanoparticle catalyzed carbonylative Suzuki–Miyaura coupling reactions under ligand-free conditions have been developed to synthesize diaryl ketones. High yields and selectivities were achieved even with low catalyst loading under atmospheric pressure of CO gas. A variety of aryl iodides and arylboronic acids could be utilized to afford the diaryl ketones in excellent yields. Moreover, the ligand-free immobilized palladium nanoparticles could be recovered by simple filtration and the catalytic activity could be maintained for several runs.
Key words
carbonylative Suzuki–Miyaura coupling - heterogeneous catalyst - palladium catalyst - nanoparticle - diaryl ketonesSupporting Information
- Supporting information for this article is available online at https://doi.org/10.1055/s-0040-1707243.
- Supporting Information
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