Metastatic prostate carcinoma in head and neck surgery: A Case Report about Prostate Cancer Metastasis in the Thyroid Gland

Introduction The thyroid gland is due to its rich vascular supply a frequent localization for malignant tumors, metastases of the prostate, however, occur very rarely in the thyroid gland. Prostate carcinoma is by far the most common malignant tumor among men (German Cancer Society). It metastasises frequently in bones, lungs, liver, pleura and kidneys.

Case report We report about a 65-year-old man who was been referred to our clinic because of dysphagia. There were pathological cervical lymph nodes, an enlarged thyroid gland and a bilateral tumor in the base of the tongue. Two months earlier a prostate carcinoma was diagnosed, at the time of presentation the patient had already undergone surgery (R1 status), metastasis was not present at that time.

Findings In the MIBI-scan of the thyroid gland a pathological nodule was found on the left side, so that a hemithyroidectomy left was performed in addition to a tissue excision of the base of the tongue. Histological findings were a squamous cell carcinoma of the oropharynx and a thyroid metastasis, matching the previously diagnosed prostate carcinoma.

Therapy In cT4 oropharyngeal carcinoma a definitive radiochemotherapy was performed. No tumor or pathological cervical lymph nodes could be detected in the final CT-scan or clinically in the oropharynx. Subsequently, hormone treatment for prostate cancer was performed.

Conclusion With this case we would like to draw your attention to the complexity as well as the extraordinary course of the disease and its management. On the one hand, it is important that the histological differentiation is correct and that the various specialist departments work together in an interdisciplinary manner regarding therapy.

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Artikel online veröffentlicht:
10. Juni 2020