Covid-19 and Pregnancy: An Overview

Pedro Castro; Ana Paula Matos; Heron Werner; Flávia Paiva Lopes; Gabriele Tonni; Edward Araujo Júnior

doi:10.1055/s-0040-1713408

Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics, Inhaltsverzeichnis

CC BY 4.0 · Rev Bras Ginecol Obstet 2020; 42(07): 420-426
DOI: 10.1055/s-0040-1713408

Review Article

Covid-19

Covid-19 and Pregnancy: An Overview

Covid-19 e gravidez: Uma visão geral

Pedro Castro

¹Department of Fetal Medicine, Clínica de Diagnóstico por Imagem, Rio de Janeiro, RJ, Brazil

²Department of Radiology, Universidade Federal do Rio de Janeiro, Rio de Janeiro, RJ, Brazil

,

Ana Paula Matos

¹Department of Fetal Medicine, Clínica de Diagnóstico por Imagem, Rio de Janeiro, RJ, Brazil

,

Heron Werner

¹Department of Fetal Medicine, Clínica de Diagnóstico por Imagem, Rio de Janeiro, RJ, Brazil

,

Flávia Paiva Lopes

¹Department of Fetal Medicine, Clínica de Diagnóstico por Imagem, Rio de Janeiro, RJ, Brazil

,

Gabriele Tonni

³Prenatal Diagnostic Service, Department of Obstetrics and Gynecology, AUSL Reggio Emilia, Italy

,

Edward Araujo Júnior

⁴Department of Obstetrics, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil

⁵Medical Course, Universidade Municipal de São Caetano do Sul, São Caetano do Sul, SP, Brazil

› Institutsangaben

Abstract

Since the World Health Organization (WHO) declared coronavirus infection (COVID-19) a Public Health Emergency of International Concern in January 2020, there have been many concerns about pregnant women and the possible effects of this emergency with catastrophic outcomes in many countries. Information on COVID-19 and pregnancy are scarce and spread throughout a few case series, with no more than 50 cases in total. The present review provides a brief analysis of COVID-19, pregnancy in the COVID-19 era, and the effects of COVID-19 on pregnancy.

Resumo

Desde que a Organização Mundial da Saúde (OMS) declarou a infecção por coronavírus (COVID-19) uma emergência de saúde pública de interesse internacional em janeiro de 2020, houve muitas preocupações sobre mulheres grávidas e os possíveis efeitos dessa emergência com resultados catastróficos em muitos países. As informações sobre COVID-19 e gravidez são escassas e se espalham por algumas séries de casos, com não mais do que 50 casos no total. A presente revisão fornece uma breve análise da COVID-19, gravidez na era COVID-19 e os efeitos da COVID-19 na gravidez.

Keywords

COVID-19 - pregnancy - prenatal care - delivery

Descritores

COVID-19 - gravidez - pré-natal - parto

Volltext

Referenzen

References
1 Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y. et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395 (10223): 497-506 . Doi: 10.1016/S0140-6736(20)30183-5
2 Coronavirus disease. 2019 (COVID-2019): situation report – 54 [Internet]. Geneva: World Health Organization; 2020. [cited 2020 Mar 15]. Available from: https://www.who.int/docs/default-source/coronaviruse/situation-reports/20200314-sitrep-54-covid-19.pdf?sfvrsn=dcd46351_8
3 Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J. et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus-infected pneumonia in Wuhan, China. JAMA 2020; •••
4 Su S, Wong G, Shi W, Liu J, Lai ACK, Zhou J. et al. Epidemiology, genetic recombination, and pathogenesis of coronaviruses. Trends Microbiol 2016; 24 (06) 490-502 . Doi: 10.1016/j.tim.2016.03.003
5 Tyrrell DA, Bynoe ML. Cultivation of viruses from a high proportion of patients with colds. Lancet 1966; 1 (7428): 76-77 . Doi: 10.1016/s0140-6736(66)92364-6
6 Tyrrell DA, Almeida JD, Cunningham CH, Dowdle WR, Hofstadt MS, McIntosh K. et al. Coronaviridae. Intervirology 1975; 5 (1-2): 76-82 . Doi: 10.1159/000149883
7 Bradburne AF, Bynoe ML, Tyrrell DA. Effects of a “new” human respiratory virus in volunteers. BMJ 1967; 3 (5568): 767-769 . Doi: 10.1136/bmj.3.5568.767
8 Bradburne AF, Somerset BA. Coronative antibody tires in sera of healthy adults and experimentally infected volunteers. J Hyg (Lond) 1972; 70 (02) 235-244 . Doi: 10.1017/s0022172400022294
9 Tyrrell DAJ, Myint SH. Coronaviruses. In: Baron S. ed. Medical microbiology. 4th ed. Galveston: University of Texas Medical Branch; 1996
10 Wong ACP, Li X, Lau SKP, Woo PCY. Global epidemiology of bat coronaviruses. Viruses 2019; 11 (02) E174 . Doi: 10.3390/v11020174
11 Han Q, Lin Q, Jin S, You L. Coronavirus 2019-nCoV: A brief perspective from the front line. J Infect 2020; 80 (04) 373-377 . Doi: 10.1016/j.jinf.2020.02.010
12 Li W, Shi Z, Yu M, Ren W, Smith C, Epstein JH. et al. Bats are natural reservoirs of SARS-like coronaviruses. Science 2005; 310 (5748): 676-679 . Doi: 10.1126/science.1118391
13 Zhou P, Yang XL, Wang XG, Hu B, Zhang L, Zhang W. et al. A pneumonia outbreak associated with a new coronavirus of probable bat origin. Nature 2020; 579 (7798): 270-273 . Doi: 10.1038/s41586-020-2012-7
14 Wang W, Tang J, Wei F. Updated understanding of the outbreak of 2019 novel coronavirus (2019-nCoV) in Wuhan, China. J Med Virol 2020; 92 (04) 441-447 . Doi: 10.1002/jmv.25689
15 Wrapp D, Wang N, Corbett KS, Goldsmith JA, Hsieh C-L, Abiona O. et al. Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation. Science 2020; 367 (6483): 1260-1263 . Doi: 10.1126/science.abb2507
16 Sun P, Lu X, Xu C, Sun W, Pan B. Understanding of COVID-19 based on current evidence. J Med Virol 2020; •••
17 Letko M, Marzi A, Munster V. Functional assessment of cell entry and receptor usage for SARS-CoV-2 and other lineage B betacoronaviruses. Nat Microbiol 2020; 5 (04) 562-569 . Doi: 10.1038/s41564-020-0688-y
18 Chan JFW, Yuan S, Kok KH, To KKW, Chu H, Yang J. et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet 2020; 395 (10223): 514-523 . Doi: 10.1016/S0140-6736(20)30154-9
19 van Doremalen N, Bushmaker T, Morris DH, Holbrook MG, Gamble A, Williamson BN. et al. Aerosol and surface stability of SARS-CoV-2 as compared with SARS-CoV-1. N Engl J Med 2020; 382 (16) 1564-1567 . Doi: 10.1056/NEJMc2004973
20 Jamieson DJ, Honein MA, Rasmussen SA, Williams JL, Swerdlow DL, Biggerstaff MS. , et al; Novel Influenza A (H1N1) Pregnancy Working Group. H1N1 2009 influenza virus infection during pregnancy in the USA. Lancet 2009; 374 (9688): 451-458 . Doi: 10.1016/S0140-6736(09)61304-0
21 Madinger NE, Greenspoon JS, Ellrodt AG. Pneumonia during pregnancy: has modern technology improved maternal and fetal outcome?. Am J Obstet Gynecol 1989; 161 (03) 657-662 . Doi: 10.1016/0002-9378(89)90373-6
22 Rigby FB, Pastorek II JG. Pneumonia during pregnancy. Clin Obstet Gynecol 1996; 39 (01) 107-119 . Doi: 10.1097/00003081-199603000-00011
23 Harris JW. Influenza occurring in pregnant women. A statistical study of thirteen hundred and fifty cases. JAMA 1919; 72 (14) 978-980 . Doi: 10.1001/jama.1919.02610140008002
24 Benedetti TJ, Valle R, Ledger WJ. Antepartum pneumonia in pregnancy. Am J Obstet Gynecol 1982; 144 (04) 413-417 . Doi: 10.1016/0002-9378(82)90246-0
25 Di Mascio D, Khalil A, Saccone G, Rizzo G, Buca D, Liberati M. et al. Outcome of Coronavirus spectrum infections (SARS, MERS, COVID 1 -19) during pregnancy: a systematic review and meta-analysis. Am J Obstet Gynecol MFM 2020; 100107: 100107 . Doi: 10.1016/j.ajogmf.2020.100107
26 Ai T, Yang Z, Hou H, Zhan C, Chong C, Lv W. et al. Correlation of chest CT and RT-PCR testing in Coronavirus Disease 2019 (COVID-19) in China: a report of 1014 cases. Radiology 2020; 200642: 200642 . Doi: 10.1148/radiol.2020200642
27 Liu D, Li L, Wu X, Zheng D, Wang J, Yang L, Zheng C. Pregnancy and perinatal outcomes of women with Coronavirus Disease (COVID-19) pneumonia: a preliminary analysis. AJR Am J Roentgenol 2020; •••: 1-6 . Doi: 10.2214/AJR.20.23072
28 Favre G, Pomar L, Qi X, Nielsen-Saines K, Musso D, Baud D. Guidelines for pregnant women with suspected SARS-CoV-2 infection. Lancet Infect Dis 2020;
29 Chen H, Guo J, Wang C, Luo F, Yu X, Zhang W. et al. Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records. Lancet 2020; 395 (10226): 809-815 . Doi: 10.1016/S0140-6736(20)30360-3
30 Lu Q, Shi Y. Coronavirus disease (COVID-19) and neonate: What neonatologist need to know. J Med Virol 2020; •••
31 Wang L, Shi Y, Xiao T, Fu J, Feng X, Mu D. , et al; Working Committee on Perinatal and Neonatal Management for the Prevention and Control of the 2019 Novel Coronavirus Infection. Chinese expert consensus on the perinatal and neonatal management for the prevention and control of the 2019 novel coronavirus infection (First edition). Ann Transl Med 2020; 8 (03) 47 . Doi: 10.21037/atm.2020.02.20
32 Qiao J. What are the risks of COVID-19 infection in pregnant women?. Lancet 2020; 395 (10226): 760-762 . Doi: 10.1016/S0140-6736(20)30365-2
33 Giwa AL, Desai A, Duca A. Novel 2019 coronavirus SARS-CoV-2 (COVID-19): An updated overview for emergency clinicians. Emerg Med Pract 2020; 22 (05) 1-28
34 Dashraath P, Wong JLJ, Lim MXK, Lim LM, Li S, Biswas A. et al. Coronavirus disease 2019 (COVID-19) pandemic and pregnancy. Am J Obstet Gynecol 2020;
35 Chen Y, Li Z, Zhang YY, Zhao WH, Yu ZY. Maternal health care management during the outbreak of coronavirus disease 2019. J Med Virol 2020; •••
36 Royal College of Obstetricians & Gynaecologists. Coronavirus (COVID-19) infection in pregnancy. Information for healthcare professionals [Internet]. London: RCOG; 2020. [cited 2020 Mar 31]. Available from: https://rcog.org.uk/coronavirus-pregnancy
37 Yu N, Li W, Kang Q, Xiong Z, Wang S, Lin X. et al. Clinical features and obstetric and neonatal outcomes of pregnant patients with COVID-19 in Wuhan, China: a retrospective, single-centre, descriptive study. Lancet Infect Dis 2020; 20 (05) 559-564 . Doi: 10.1016/S1473-3099(20)30176-6
38 Lee DH, Lee J, Kim E, Woo K, Park HY, An J. Emergency cesarean section on severe acute respiratory syndrome coronavirus 2 (SARS- CoV-2) confirmed patient. Korean J Anesthesiol 2020; •••
39 Kang X, Zhang R, He H, Yao Y, Zheng Y, Wen X. et al. [Anesthesia management in cesarean section for a patient with coronavirus disease 2019]. Zhejiang Da Xue Xue Bao Yi Xue Ban 2020; 49 (02) 249-252
40 Chen S, Liao E, Cao D, Gao Y, Sun G, Shao Y. Clinical analysis of pregnant women with 2019 novel coronavirus pneumonia. J Med Virol 2020; •••
41 Sahu KK, Lal A, Mishra AK. COVID-2019 and pregnancy: A plea for transparent reporting of all cases. Acta Obstet Gynecol Scand 2020; •••
42 Sheahan TP, Sims AC, Graham RL, Menachery VD, Gralinski L, Case JB. et al. Broad-spectrum antiviral GS-5734 inhibits both epidemic and zoonotic coronaviruses. Sci Transl Med 2017; 9 (396) eaal3653 . Doi: 10.1126/scitranslmed.aal3653
43 Zhou D, Dai SM, Tong Q. COVID-19: a recommendation to examine the effect of hydroxychloroquine in preventing infection and progression. J Antimicrob Chemother 2020; •••: dkaa114 . Doi: 10.1093/jac/dkaa114
44 Lim J, Jeon S, Shin HY, Kim MJ, Seong YM, Lee WJ. et al. Case of the index patient who caused tertiary transmission of COVID-19 infection in Korea: the application of lopinavir/ritonavir for the treatment of COVID-19 infected pneumonia monitored by quantitative RT-PCR. J Korean Med Sci 2020; 35 (06) e79 . Doi: 10.3346/jkms.2020.35.e79
45 Bhatnagar T, Murhekar MV, Soneja M, Gupta N, Giri S, Wig N, Gangakhedar R. et al. Lopinavir/ritonavir combination therapy amongst symptomatic coronavirus disease 2019 patients in India: Protocol for restricted public health emergency use. Indian J Med Res 2020; 151 (2 & 3): 184-189 . Doi: 10.4103/ijmr.IJMR_502_20
46 Yang H, Wang C, Poon LC. Novel coronavirus infection and pregnancy. Ultrasound Obstet Gynecol 2020; 55 (04) 435-437 . Doi: 10.1002/uog.22006
47 Donati S, Giusti A, Zambri F, Marchetti F, Sampaolo L. COVID-19 in gravidanza, parto e allattamento: gli aggiornamenti nazionali e internazionali della settimana 9–16 aprile 2020 [Internet]. Roma: EpiCentro - Istituto Superiore di Sanità; 2020. [cited 2020 Apr 30]. Available from: https://www.epicentro.iss.it/coronavirus/sars-cov-2-gravidanza-parto-allattamento-16-4-20
48 Li Y, Zhao R, Zheng S, Chen X, Wang J, Sheng X. et al. Lack of Vertical Transmission of Severe Acute Respiratory Syndrome Coronavirus 2, China. Emerg Infect Dis 2020; 26 (06)
49 Schwartz DA, Graham AL. Potential maternal and infant outcomes from (Wuhan) Coronavirus 2019-nCoV infecting pregnant women: lessons from SARS, MERS, and other human coronavirus infections. Viruses 2020; 12 (02) E194 . Doi: 10.3390/v12020194
50 Liang H, Acharya G. Novel corona virus disease (COVID-19) in pregnancy: What clinical recommendations to follow?. Acta Obstet Gynecol Scand 2020; 99 (04) 439-442 . Doi: 10.1111/aogs.13836
51 Zheng QL, Duan T, Jin LP. Single-cell RNA expression profiling of ACE2 and AXL in the human maternal-fetal interface. Reprod Dev Med [Internet]. 2020 [cited 2020 Mar 31];4(1):7–10. Available from: http://www.repdevmed.org/text.asp?2020/4/1/7/278679
52 Remuzzi A, Remuzzi G. COVID-19 and Italy: what next?. Lancet 2020; 395 (10231): 1225-1228 . Doi: 10.1016/S0140-6736(20)30627-9
53 Zhu H, Wang L, Fang C, Peng S, Zhang L, Chang G. et al. Clinical analysis of 10 neonates born to mothers with 2019-nCoV pneumonia. Transl Pediatr 2020; 9 (01) 51-60 . Doi: 10.21037/tp.2020.02.06
54 Liu Y, Chen H, Tang K, Guo Y. Clinical manifestations and outcome of SARS-CoV-2 infection during pregnancy. J Infect 2020; ; pii: S0163–4453(20)30109–2.
55 Hick JL, Biddinger PD. Novel Coronavirus and old lessons - preparing the health system for the pandemic. N Engl J Med 2020; 382 (20) e55 . Doi: 10.1056/NEJMp2005118
56 Gao L, Zhang J. Pulmonary High-Resolution Computed Tomography (HRCT) Findings of Patients with Early-Stage Coronavirus Disease 2019 (COVID-19) in Hangzhou, China. Med Sci Monit 2020; 26: e923885 . Doi: 10.12659/MSM.923885
57 Castro P, Narciso C, Matos AP, Werner H, Araujo Júnior E. Pregnant, uninfected, stressed, and confined in the COVID-19 period: what can we expect in the near future?. Rev Bras Med Assoc 2020; 66 (03) 100-101