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Journal of Pediatric Neurology 2021; 19(06): 389-394
DOI: 10.1055/s-0040-1714094
Original Article

Pediatric Neuromuscular Disorders in Ile-Ife, Nigeria: Pattern and the Challenges with Management

Oluwatosin E. Olorunmoteni 
1   Department of Pediatrics and Child Health, Obafemi Awolowo University, Ile-Ife, Nigeria
,
Abiodun J. Kareem
1   Department of Pediatrics and Child Health, Obafemi Awolowo University, Ile-Ife, Nigeria
,
Musa Ayogu
1   Department of Pediatrics and Child Health, Obafemi Awolowo University, Ile-Ife, Nigeria
› Author Affiliations Funding None.
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Abstract

The aim of this study was to describe the presentation pattern and challenges with the management of pediatric neuromuscular disorders (NMDs) in Ile-Ife, Nigeria through retrospective review of their clinical records. We recruited 24 children aged 14 days to 15 years with a male preponderance (male-to-female ratio = 2.4:1). Late presentation was a prominent feature which was highest among children with myopathies with a mean duration of symptoms of 46.5 ± 33.4 months before presentation. Peripheral neuropathy was the most common type of NMDs (63.0%). Among these, injection nerve palsy from the use of wrong site for intramuscular injections was the most common (60.0%). Nonavailability of electrophysiologic and genetic testing as well as appropriate medications was the major challenges. Acquired NMDs are common in our setting. There is a need to improve preventive measures of acquired NMDs and early diagnosis of the inherited types.

Keywords

neuromuscular disease - peripheral neuropathy - muscular dystrophy - childhood


Publication History

Received: 07 February 2020

Accepted: 29 May 2020

Article published online:
05 August 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
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