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CC BY 4.0 · Aorta (Stamford) 2020; 08(04): 091-097
DOI: 10.1055/s-0040-1715588
State-of-the-Art Review

Modeling of the Aorta: Complexities and Inadequacies

Kumbakonam R. Rajagopal 
1   Department of Mechanical Engineering, Texas A&M University, College Station, Texas
,
Keshava Rajagopal
2   Department of Clinical Sciences, University of Houston College of Medicine, Houston, Texas
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Funding None.
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Abstract

The aorta is a very complex organ comprising three layers, consisting of four kinds of tissues. It is an anisotropic, inhomogeneous, multiconstituent, and living organ that presents both a formidable challenge and a tremendous opportunity to a modeler to mathematically characterize its structure. Unfortunately, even the most sophisticated models in vogue do not faithfully take into consideration its various complexities, falling very short of putting into place a reasonable model, as they ignore many of the quintessential features that need to be taken into account. In this article, we address the various features that need to be taken into account to develop a meaningful model of the aorta.

Keywords

aorta - viscoelasticity - anisotropy - inhomogeneity - mixture - fluid–solid interaction


Publication History

Received: 23 February 2020

Accepted: 12 June 2020

Article published online:
11 December 2020

© 2020. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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