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CC BY-NC-ND 4.0 · Journal of Digestive Endoscopy 2021; 12(04): 249-252
DOI: 10.1055/s-0040-1716449
Case Report

CMV Disease of Upper GI Tract in Immunocompetent Host: Two Case Reports and Brief Review of Literature

Nikhil Mahajan
1   Department of Gastroenterology, Shrimann Hospital, Jalandhar, Punjab, India
2   Department of Gastroenterology, Medanta-The Medicity, Gurugram, Haryana, India
,
Aproo Sharma
3   Department of Pathology, AFCME, New Delhi, India
,
Mukesh Nasa
1   Department of Gastroenterology, Shrimann Hospital, Jalandhar, Punjab, India
,
Lipika Lipi
4   Department of Gastro-Pathology, Medanta-The Medicity, Gurugram, Haryana, India
,
Rini Sharma
5   Department of Pathology, ASCOMS, Jammu, J & K, India
,
Navleen Arora
6   Department of Pathology, Shrimann Hospital, Jalandhar, Punjab, India
,
Balwinder Singh
1   Department of Gastroenterology, Shrimann Hospital, Jalandhar, Punjab, India
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Abstract

Gastrointestinal cytomegalovirus (GI-CMV) infection is well-reported in immunocompromised individuals and those on chemotherapy or other immunosuppressive medications. Rarely, CMV infection of gastrointestinal tract (GIT) occurs in immunocompetent individuals. Colon is the most common site of GI involvement with CMV. However, in immunocompetent individuals, upper GIT involvement is more common. Clinical spectrum of GI-CMV disease is variable and depends on the location and severity of the disease. Prompt diagnosis and treatment aids in reducing morbidity and mortality related to CMV involvement in GI tract. We present two interesting cases of CMV-induced GI ulcers in immunocompetent individuals with brief review of diagnostic and treatment challenges associated with CMV disease in immunocompetent individuals.

Keywords

cytomegalovirus (CMV) - esophageal ulcer - gastric ulcer - immunocompetent - upper gastrointestinal tract


Publication History

Article published online:
28 December 2020

© 2022. Society of Gastrointestinal Endoscopy of India. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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