RSS-Feed abonnieren
DOI: 10.1055/s-0040-1718965
Does Caffeine Intake Increase the Incidence of Tinnitus? A Systematic Review
Abstract
Introduction Excessive caffeine intake has been thought to be a contributory factor for tinnitus. However, there has been no systematic review to elucidate the causal relationship between caffeine intake and the incidence of tinnitus.
Objectives We performed the current review aiming at evaluating the evidence from the current literature for the relationship between caffeine intake and the incidence of tinnitus.
Data Synthesis Databases including PubMed, Scopus, and Google scholar were searched for relevant articles. A total of 142 studies were screened for eligibility, of which four articles met our inclusion criteria: two were prospective cohorts and two were cross-sectional studies. Although one study found no association between caffeine consumption and the incidence of tinnitus, an inverse relationship was reported by two population-based studies. Concerning patients with preexisting tinnitus, reduction of caffeine intake in a subset who consumed 150 ml to 300 ml/day of coffee yielded a favorable outcome in tinnitus severity. However, those with higher dose intake were less prone to have improvement in the severity of tinnitus.
Conclusion Although the current review was inconclusive, it appears that the incidence of tinnitus in previously unaffected individuals might be prevented by a high dose of caffeine intake. However, in preexisting tinnitus, a high dose of caffeine may adversely interfere with the efficacy of caffeine reduction.
Authors' Contributions
Sattam M. Aljuaid: Conception; critical revision for important intellectual content; final approval of the version to be published
Ahmad A. Mirza: Conception; drafting the work; critical revision for important intellectual content; final approval of the version to be published
Lura A. Habib: Drafting the work; final approval of the version to be published
Lujain A. AlHarthi: Drafting the work; final approval of the version to be published
Bashayer M. Alansari: Drafting the work; final approval of the version to be published
Bashaier G. AlQahtani: Drafting the work; final approval of the version to be published
Youssef A. Althobaiti: Drafting the work; final approval of the version to be published
Publikationsverlauf
Eingereicht: 15. Juni 2020
Angenommen: 01. September 2020
Artikel online veröffentlicht:
30. November 2020
© 2020. Fundação Otorrinolaringologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)
Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil
-
References
- 1 Kim HJ, Lee HJ, An SY. et al. Analysis of the prevalence and associated risk factors of tinnitus in adults. PLoS One 2015; 10 (05) e0127578
- 2 McCormack A, Edmondson-Jones M, Somerset S, Hall D. A systematic review of the reporting of tinnitus prevalence and severity. Hear Res 2016; 337: 70-79
- 3 Heller AJ. Classification and epidemiology of tinnitus. Otolaryngol Clin North Am 2003; 36 (02) 239-248
- 4 Hoare DJ, Kowalkowski VL, Kang S, Hall DA. Systematic review and meta-analyses of randomized controlled trials examining tinnitus management. Laryngoscope 2011; 121 (07) 1555-1564
- 5 Onishi ET, Coelho CCB, Oiticica J. et al. Tinnitus and sound intolerance: evidence and experience of a Brazilian group. Braz J Otorhinolaryngol 2018; 84 (02) 135-149
- 6 Pujol R, Puel JL. Excitotoxicity, synaptic repair, and functional recovery in the mammalian cochlea: a review of recent findings. Ann N Y Acad Sci 1999; 884: 249-254
- 7 Sepkowitz KA. Energy drinks and caffeine-related adverse effects. JAMA 2013; 309 (03) 243-244
- 8 John J, Kodama T, Siegel JM. Caffeine promotes glutamate and histamine release in the posterior hypothalamus. Am J Physiol Regul Integr Comp Physiol 2014; 307 (06) R704-R710
- 9 Cappelletti S, Piacentino D, Sani G, Aromatario M. Caffeine: cognitive and physical performance enhancer or psychoactive drug?. Curr Neuropharmacol 2015; 13 (01) 71-88
- 10 Ledesma AL, Barreto MA, Bahmad Jr F. Caffeine effect in vestibular system. Int Tinnitus J 2014; 19 (01) 77-81
- 11 Marmut Z, Belojevic G, Backovic D, Zivojinovic JI, Tomanic M, Hadzic E. Tinnitus among Serbian secondary school students in relation to their behavior and habits. Noise Health 2014; 16 (69) 73-78
- 12 Lee SY, Jung G, Jang MJ. et al. Association of Coffee Consumption with Hearing and Tinnitus Based on a National Population-Based Survey. Nutrients 2018; 10 (10) 1429
- 13 Schmidt Rosito LP, Vanni B, Deutsch K, de Brito Belline V. Would Caffeine Consumption Have Some Effect on the Perception of Tinnitus?. Otolaryngol Head Neck Surg 2011; 145 (2_suppl): P233-P233
- 14 Figueiredo RR, Rates MJ, Azevedo AA, Moreira RK, Penido NdeO. [Effects of the reduction of caffeine consumption on tinnitus perception]. Braz J Otorhinolaryngol 2014; 80 (05) 416-421
- 15 Glicksman JT, Curhan SG, Curhan GC. A prospective study of caffeine intake and risk of incident tinnitus. Am J Med 2014; 127 (08) 739-743
- 16 McCormack A, Edmondson-Jones M, Mellor D. et al. Association of dietary factors with presence and severity of tinnitus in a middle-aged UK population. PLoS One 2014; 9 (12) e114711
- 17 Trinidade A, Robinson T, Phillips JS. The role of caffeine in otorhinolaryngology: guilty as charged?. Eur Arch Otorhinolaryngol 2014; 271 (08) 2097-2102
- 18 Nehlig A, Daval JL, Debry G. Caffeine and the central nervous system: mechanisms of action, biochemical, metabolic and psychostimulant effects. Brain Res Brain Res Rev 1992; 17 (02) 139-170
- 19 Claire LS, Stothart G, McKenna L, Rogers PJ. Caffeine abstinence: an ineffective and potentially distressing tinnitus therapy. Int J Audiol 2010; 49 (01) 24-29