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Journal of Pediatric Neurology 2021; 19(06): 425-427
DOI: 10.1055/s-0040-1721380
Case Report

Dexmedetomidine Infusion as a Novel Supportive Therapy for Fluphenazine-Induced Neuroleptic Malignant Syndrome in a 10-Year-Old Boy: A Case Report and Review of Literature

Caroline Yu
1   Department of Pediatrics, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, United States
,
Rajat Kaul
2   Department of Pediatrics, Division of Pediatric Hospitalist Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, United States
,
Waseem Ostwani
3   Department of Pediatrics, Division of Pediatric Critical Care Medicine, University of Toledo College of Medicine and Life Sciences, Toledo, Ohio, United States
› Institutsangaben Funding None.
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Abstract

A 10-year-old male child patient developed symptoms of neuroleptic malignant syndrome (NMS) 1 month following initiation of fluphenazine for behavioral therapeutic management. Dexmedetomidine infusion was able to adequately control the symptoms of NMS with resolution of encephalopathy. This was the first report of novel dexmedetomidine utilization for the treatment of NMS. We suggest using dexmedetomidine as an adjunctive agent to control NMS symptomatology without attendant risk of respiratory depression.

Keywords

neuroleptic malignant syndrome - fluphenazine - dexmedetomidine


Publikationsverlauf

Eingereicht: 03. Oktober 2020

Angenommen: 21. Oktober 2020

Artikel online veröffentlicht:
18. Dezember 2020

© 2020. Thieme. All rights reserved.

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 

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