Abstract
Background Pancreaticopleural fistulas are among the rarest complications of chronic pancreatitis.
The main objective of the research, conducted on a total of seven patients, was to
evaluate the effectiveness of early endoscopic management of pancreaticopleural fistula.
Methods The diagnosis of fistula was reached when fistulous tract was demonstrated on imaging
studies and/or pleural fluid amylase level was greater than 2,000 U/L. The data were
retrospectively analyzed from the records.
Results The prototype patient in our series was a chronic alcoholic male with median age
of 45 years. Computed tomography scan was performed in all the seven patients but
could diagnose leak only in four patients. Magnetic resonance cholangiopancreatography
was better in the remaining three patients for diagnosing fistula. Endoscopic retrograde
cholangiopancreatography was the most sensitive test that diagnosed fistula in all
the seven patients. Pancreatic duct (PD) cannulation was successful and pancreatic
sphincterotomy with PD stenting was performed in all the seven patients. We could
avoid surgical intervention in our patients.
Conclusions We advise early endoscopic treatment within 7 days of symptom onset as opposed to
3 weeks, which was proposed previously. Medical therapies should be complimentary
to PD stenting.
Keywords
pancreaticopleural fistula - early endoscopic management of pancreaticopleural fistula
- chronic pancreatitis - pancreatic ductal leak
