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CC BY 4.0 · TH Open 2021; 05(01): e8-e13
DOI: 10.1055/s-0040-1721733
Review Article

Autoimmune Hemolytic Anemia and Pulmonary Embolism: An Association to Consider

Daria Solari
1   Division and Central Laboratory of Hematology, Department of Oncology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
,
Lorenzo Alberio 
1   Division and Central Laboratory of Hematology, Department of Oncology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
,
Camillo Ribi 
2   Division of Immunology and Allergy, Department of Medicine, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
,
Francesco Grandoni 
1   Division and Central Laboratory of Hematology, Department of Oncology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
,
Gregoire Stalder 
1   Division and Central Laboratory of Hematology, Department of Oncology, Lausanne University Hospital (CHUV) and University of Lausanne (UNIL), Lausanne, Switzerland
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Abstract

Autoimmune hemolytic anemia (AIHA) is increasingly recognized as a strong risk factor for venous thrombosis. However, there are currently no guidelines on thromboembolism prevention and management during AIHA. Here, we describe the case of a patient with AIHA and pulmonary embolism and resume the current knowledge on epidemiology, risk factors, treatment, and pathophysiology of thrombosis during AIHA, as well as new therapeutic perspectives to prevent thrombus formation during AIHA.

Keywords

anticoagulant prophylaxis - autoimmune hemolytic anemia - complication - venous thromboembolism

Note

Signed informed consent was obtained from the patient included in this work.


Authors' Contributions

D.S. and G.S. conceived the study, performed the literature research, and prepared the manuscript. L.A., C.R., and F.G. wrote, commented, and corrected the manuscript.




Publication History

Received: 03 June 2020

Accepted: 05 November 2020

Article published online:
17 January 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

Georg Thieme Verlag KG
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