Abstract
Objective To describe the epidemiological and clinical profile of patients with Dupuytren disease
treated by selective fasciectomy and the factors associated with the severity of the
disease.
Methods Retrospective descriptive observational study involving 247 patients with Dupuytren
disease, from 2013 to 2019. Multivariate logistic regression was performed for data
analysis.
Results Most patients were male (83.8%), self-declared white (65.2%), alcoholics (59.6%)
and 49% were smokers, with a mean age of 66 ± 9 years old, with 77.2% presenting symptoms
of the disease after the age of 51 years old. Approximately 51.9, 29.6 and 17.3%,
respectively, had arterial hypertension, diabetes mellitus and dyslipidemia comorbidities.
Bilateral involvement of the hands was observed in 73.3% of the patients. The rate
of intra- and post-selective fasciectomy complications was of 0.6 and 24.3%, respectively,
with 5.2% of the patients needing reintervention after 1 year of follow-up. After
multivariate analysis, males were associated with bilateral involvement of the hands
(odds ratio [OR] = 2.10; 95% confidence interval [CI]: 1.03–4.31) and with a greater
number of affected rays (OR = 3.41; 95% CI: 1.66–7.03). Dyslipidemia was associated
with reintervention (OR = 5.7; 95% CI = 1.03–31.4) and bilaterality with a higher
number of complications (35.7 versus 19.7%).
Conclusion A low rate of reintervention and operative complications was observed in patients
with Dupuytren disease treated by selective fasciectomy. Male gender was associated
with severe disease (bilaterality and more than two affected rays), and dyslipidemia
with reintervention.
Keywords
dupuytren disease - fasciectomy - risk factors - operative complications - reintervention
