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Dtsch Med Wochenschr 2015; 140(07): 496-499
DOI: 10.1055/s-0041-101153
DOI: 10.1055/s-0041-101153
Klinischer Fortschritt
Nephrologie
Primäre arterielle Hypertonie – Update 2015
Primary arterial hypertension – update 2015Further Information
Publication History
Publication Date:
31 March 2015 (online)
![](https://www.thieme-connect.de/media/dmw/201507/lookinside/thumbnails/10.1055-s-0041-101153-1.jpg)
Zusammenfassung
Epidemiologische Untersuchungen zeigen für Deutschland eine deutlich bessere Behandlungsrate und Kontrolle der arteriellen Hypertonie. Ein Zusammenhang zwischen Kochsalzkonsum und Höhe von systolischem und diastolischem Blutdruck konnte nachgewiesen werden. Für die therapeutischen Optionen bleibt der Stellenwert der renalen Denervierung noch unklar.
Abstract
The rate of treatment and control increased significantly in Germany during the last years. Severeal studies could demonstrate an association of sodium consumption with blood pressure. The status of renal denervation in the treatment of high blood pressure remains unclear.
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Literatur
- 1 Acelajado MC, Pisoni R, Dudenbostel T et al. Refractory hypertension: definition, prevalence, and patient characteristics. J Clin Hypertens (Greenwich) 2012; 14: 7-12
- 2 Bhatt DL, Kandzari DE, O’Neill WW et al. A controlled trial of renal denervation for resistant hypertension. N Engl J Med 2014; 370: 1393-1401
- 3 Brinkmann J, Heusser K, Schmidt BM et al. Catheter-based renal nerve ablation and centrally generated sympathetic activity in difficult-to-control hypertensive patients: prospective case series. Hypertension 2012; 60: 1485-1490
- 4 Diederichs C, Neuhauser H. Regional variations in hypertension prevalence and management in Germany: results from the German Health Interview and Examination Survey (DEGS1). J Hypertens 2014; 32: 1405-1414
- 5 Esler MD, Krum H, Sobotka P et al. Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial. Lancet 2010; 376: 1903-1909
- 6 Graudal NA, Hubeck-Graudal T, Jurgens G. Effects of low-sodium diet vs. high-sodium diet on blood pressure, renin, aldosterone, catecholamines, cholesterol, and triglyceride (Cochrane Review). Am J Hypertens 2012; 25: 1-15
- 7 Hering D, Marusic P, Walton AS et al. Sustained sympathetic and blood pressure reduction 1 year after renal denervation in patients with resistant hypertension. Hypertension 2014; 64: 118-124
- 8 Krum H, Schlaich MP, Sobotka PA et al. Percutaneous renal denervation in patients with treatment-resistant hypertension: final 3-year report of the Symplicity HTN-1 study. Lancet 2014; 383: 622-629
- 9 Mahfoud F, Vonend O, Bruck H et al. Interventionelle renale Sympathikusdenervation zur Behandlung der therapieresistenten Hypertonie. Dtsch Med Wochenschr 2011; 136: 2418
- 10 Mancia G, Fagard R, Narkiewicz K et al. 2013 ESH / ESC Guidelines for the management of arterial hypertension: the Task Force for the management of arterial hypertension of the European Society of Hypertension (ESH) and of the European Society of Cardiology (ESC). J Hypertens 2013; 31: 1281-1357
- 11 McManus RJ, Mant J, Haque MS et al. Effect of self-monitoring and medication self-titration on systolic blood pressure in hypertensive patients at high risk of cardiovascular disease: the TASMIN-SR randomized clinical trial. JAMA 2014; 312: 799-808
- 12 McMurray JJ, Packer M, Desai AS et al. Angiotensin-Neprilysin Inhibition versus Enalapril in Heart Failure. N Engl J Med 2014; 371: 993-1004
- 13 Mente A, O’Donnell MJ, Rangarajan S et al. Association of urinary sodium and potassium excretion with blood pressure. N Engl J Med 2014; 371: 601-611
- 14 Mozaffarian D, Fahimi S, Singh GM et al. Global sodium consumption and death from cardiovascular causes. N Engl J Med 2014; 371: 624-634
- 15 Neuhauser HK, Adler C, Rosario AS et al. Hypertension prevalence, awareness, treatment and control in Germany 1998 and 2008–11. J Hum Hypertens 2014;
- 16 O’Donnell MJ, Mente A, Rangarajan S et al. Urinary sodium and potassium excretion, mortality, and cardiovascular events. N Engl J Med 2014; 371: 612-623
- 17 Oparil S. Low Sodium Intake – Cardiovascular Health Benefit or Risk?. N Engl J Med 2014; 371: 677-679
- 18 Sundström J, Arima H, Woodward M et al. Blood pressure-lowering treatment based on cardiovascular risk: a meta-analysis of individual patient data. Lancet 2014; 384: 591-599
- 19 Vonend O, Böhm M, Eckert S et al. Renale Denervation bei nicht-kontrollierter arterieller Hypertonie. Dtsch Med Wochenschr 2015; 140: 363