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DOI: 10.1055/s-0041-110068
Herzerkrankungen in der Schwangerschaft
Cardiovascular disease in pregnancyPublication History
Publication Date:
22 January 2016 (online)
Zusammenfassung
Kardiovaskuläre Erkrankungen bei werdenden Müttern sind häufig. Wir fassen kurz den aktuellen Wissensstand zu Schwangerschaften zusammen, die durch präexistente maternale Herzerkrankungen kompliziert werden. Wir erklären, weshalb die Schwangerschaft ein Stressmodel für das kardiovaskuläre System ist und wie sich dies bei präexistenten Kardiomyopathien auswirkt. Ausführlich behandeln wir hypertensive Komplikationen in der Schwangerschaft und die peripartale Kardiomyopathie im Hinblick auf Ätiologie, Risikofaktoren, Pathophysiologie, Diagnose, Behandlungskonzept und Prognose. Zum Schluss legen wir dar, dass kardiovaskuläre Erkrankungen in der Schwangerschaft immer interdisziplinär betrachtet werden sollten, um eine gute Heilung der Mutter und möglichst keine Schädigung des Fötus zu erreichen
Abstract
Cardiovascular diseases are among the most frequent complications in pregnancies. Among them preexisting heart diseases including congenital heart disease, genetic cardiomyopathies, myocardial infarction and chemotherapy-induced cardiomyopathies display a special challenge for the mother and her physicians. Moreover, the incidence of cardiovascular disease induced by or associated with pregnancy, i.e. hypertensive disorders and peripartum cardiomyopathies, has increased over the past decades. In the present overview we explain why pregnancy is a stress model for the maternal heart and summarize the current knowledge on the influence of pregnancy on preexisting cardiomyopathies. We highlight recent advances in research with regard to hypertensive complications in pregnancy and peripartum cardiomyopathy (PPCM). Moreover, we summarize etiologies, risk factors, pathomechanisms, diagnosis, treatment, management and prognosis. Finally, interdisciplinarity between different clinical fields and basic science is a key requirement to avoid longterm damage to the cardiovascular system induced by pregnancy associated impacts and with this improve women‘s health in general.
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