Subscribe to RSS
Download PDF
DOI: 10.1055/s-0041-1723924
Spontaneous Perinephric Urinoma Secondary to Drug Induced Acute Interstitial Nephritis: A Case Report
Abstract
Urinoma is defined as the extravasation of urine from any part of the urinary collecting system, which causes lipolysis of the surrounding fat, resulting in an encapsulated collection. The most common cause of urinoma is the direct obstruction of the urinary system. The other etiologies include trauma and postinstrumentation/surgery. Parenchymal cause for spontaneous urinoma is exceedingly rare. We present a case of a 30-year-old gentleman who presented with lower abdominal pain and was treated with a Diclofenac injection. The pain got better temporarily, but he presented again with right loin pain after 3 days. His computed tomography scan images revealed bilateral perinephric urinoma. As there was significant deterioration of renal function, he underwent a renal biopsy. The histopathology was reported as acute interstitial nephritis (AIN). Drug-induced AIN is very rarely presented with acute loin or abdominal pain due to spontaneous perinephric urinoma, as it was seen in our case.
Keywords
spontaneous urinoma - NSAID-induced Nephritis - acute kidney injury - acute interstitial nephritisPublication History
Article published online:
25 March 2021
© 2021. Indian Society of Gastrointestinal and Abdominal Radiology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India
-
References
- 1 Chang HW, Kuei CH, Tseng CF, Hou YC, Tseng YL. Spontaneous perirenal urinoma induced by NSAID-associated acute interstitial nephritis. Ther Clin Risk Manag 2018; 14: 595-599
- 2 Wani NA, Mir F, Gojwari T, Qureshi UA, Ahmad R. Subcapsular fluid collection: an unusual manifestation of nephrotic syndrome. Am J Kidney Dis 2010; 56 (01) 181-184
- 3 Yalcin AU, Akcar N, Can C, Kasapoglu E, Sahin G. An unusual presentation for nephrotic syndrome. Bilateral perirenal subcapsular fluid collection. Nephron 2002; 92 (01) 244-245
- 4 Yilmaz S, Zor M, Ersan M, Hamcan S. Bilateral massive perirenal subcapsular effusion: A case report. J Clin Ultrasound 2017; 45 (09) 597-599
- 5 Dixit M, Doan T, Kirschner R, Dixit N. Significant acute kidney injury due to non-steroidal anti-inflammatory drugs: inpatient setting. Pharmaceuticals (Basel) 2010; 3 (04) 1279-1285
- 6 Naughton CA. Drug-induced nephrotoxicity. Am Fam Physician 2008; 78 (06) 743-750
- 7 Haddad MC, Medawar WA, Hawary MM, Khoury NJ, Ammouri NF, Shabb NS. Perirenal fluid in renal parenchymal medical disease (‘floating kidney’): clinical significance and sonographic grading. Clin Radiol 2001; 56 (12) 979-983
- 8 Seeger H, Bonani M, Segerer S. The role of lymphatics in renal inflammation. Nephrol Dial Transplant 2012; 27 (07) 2634-2641
- 9 Lang EK, Glorioso III L. Management of urinomas by percutaneous drainage procedures. Radiol Clin North Am 1986; 24 (04) 551-559