Endoscopy 2021; 53(S 01): S68
DOI: 10.1055/s-0041-1724424
Abstracts | ESGE Days
ESGE Days 2021 Oral presentations
Saturday, 27 March 2021 09:00 – 09:45 EUS for drainage of infected collections Room 6

EUS-Guided Gallbladder Drainage Using A Lumen-Apposing Metal Stent for Acute Cholecystitis: Results of A Multicenter Study

C Binda
1   AUSL Romagna, Gastroenterology and Digestive Endoscopy Unit, Forlì-Cesena Hospitals, Forlì-Cesena, Italy
,
A Anderloni
2   Humanitas Clinical and Research Center - IRCCS, Digestive Endoscopy Unit, Rozzano (MI), Italy
,
E Forti
3   Ospedale Ca’ Granda Niguarda, Digestive and Interventional Endoscopy Unit, Milano, Italy
,
P Fusaroli
4   University of Bologna, Gastroenterology Unit, Hospital of Imola (BO), Imola (BO), Italy
,
R Macchiarelli
5   A.O.U.S. Policlinico S.Maria alle Scotte, Gastroenterology Unit, Siena, Italy
,
M Manno
6   Azienda USL di Modena, UOSD Gastroenterologia ed Endoscopia Digestiva, Rete Gastroenterologica Provinciale, Modena, Italy
,
A Fugazza
2   Humanitas Clinical and Research Center - IRCCS, Digestive Endoscopy Unit, Rozzano (MI), Italy
,
A Redaelli
7   San Gerardo Hospital, Endoscopy Unit, Monza, Italy
,
G Aragona
8   Guglielmo da Saliceto Hospital, Gastroenterology and Hepatology Unit, Piacenza, Italy
,
M Lovera
9   Fondazione Poliambulanza Istituto Ospedaliero, Digestive Endoscopy Unit, Brescia, Italy
,
T Togliani
10   ASST Carlo Poma, Gastroenterology and Endoscopy Unit, Mantova, Italy
,
E Armellini
11   ASST Bergamo Est, Digestive Endoscopy Unit, Seriate, Bergamo, Italy
,
A Amato
12   Valduce Hospital, Department of Gastroenterology, Como, Italy
,
ML Brancaccio
13   S. Maria delle Croci Hospital, Division of Gastroenterology, Ravenna, Italy
,
R Badas
14   University Hospital, Digestive Endoscopy Unit, Cagliari, Italy
,
N Leone
15   Humanitas Gradenigo, Digestive Endoscopy Unit, Torino, Italy
,
G de Nucci
16   ASST Rhodense, Gastroenterology and Endoscopy Unit, Garbagnate Milanese (MI), Italy
,
B Mangiavillano
17   Humanitas - Mater Domini, Gastrointestinal Endoscopy Unit, Castellanza, Italy
,
M Sbrancia
1   AUSL Romagna, Gastroenterology and Digestive Endoscopy Unit, Forlì-Cesena Hospitals, Forlì-Cesena, Italy
,
V Pollino
18   S. Michele Hospital, Digestive Endoscopy Unit, Cagliari, Italy
,
M Maida
19   S. Elia-Raimondi Hospital, Gastroenterology and Endoscopy Unit, Caltanissetta, Italy
,
E Sinagra
20   Fondazione Istituto G. Giglio, Gastroenterology and Endoscopy Unit, Cefalù, Italy
,
A Repici
2   Humanitas Clinical and Research Center - IRCCS, Digestive Endoscopy Unit, Rozzano (MI), Italy
21   Humanitas University, Department of Biomedical Sciences, Pieve Emanuele, Milano, Italy
,
C Fabbri
1   AUSL Romagna, Gastroenterology and Digestive Endoscopy Unit, Forlì-Cesena Hospitals, Forlì-Cesena, Italy
,
I Tarantino
22   IRCCS-ISMETT, Endoscopy Service, Department of Diagnostic and Therapeutic Services, Palermo, Italy
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Aims The aim of the study is the evaluation of the effectiveness and safety of endoscopic ultrasound guided gallbladder drainage (EUS-GBD) using lumen apposing metal stents (LAMS) for acute cholecystitis (AC) in a large cohort of patients at high-risk for cholecystectomy.

Methods This is a multicenter, retrospective study including EUS-guided GBD using LAMS performed in fragile patients with AC in 19 Italian Centers from June 2014 to July 2020. Primary outcomes were technical and clinical success, secondary outcome was adverse events (AEs) rate.

Results A total of 116 patients (48.3 % female) were included, with a mean age of 82.7 ± 11 years. The mean gallbladder major axis was 71.2 ± 35.8 mm, while the mean width was 59.4 ± 34 mm. LAMS were placed transgastric in 44.8 % of cases, transduodenal in 53.3 % and transjejunal in 1.7 % in patient with altered anatomy. Technical and clinical success were achieved in 93.1 % and 87.1 % of cases respectively. In particular, white blood cell (WBC) count, C reactive protein (CRP), total and direct bilirubin levels were statistically significant reduced (p<0.05) after two weeks. The mean procedure time was 24.5 minutes. Mean hospital stay was 11.2 ± 9 days. The mean follow-up was 186.4 days. AEs occurred in 12/116 pts (10.3 %): 8/12 were intraprocedural, while 1 was classified as early (< 15 days) and 3 as delayed (> 15 days). According to ASGE lexicon, 2 (16.7 %) were mild, 3 (25 %) were moderate, while 7 (58.3 %) were severe.

Conclusions Our study shows that EUS-GBD had high technical and clinical success rates in a large cohort of fragile patients. Although the not negligible rate of AEs, EUS-guided GBD should be considered an effective option of treatment in inoperable patients.

Citation: Binda C, Anderloni A, Forti E et al. OP167 EUS-GUIDED GALLBLADDER DRAINAGE USING A LUMEN-APPOSING METAL STENT FOR ACUTE CHOLECYSTITIS: RESULTS OF A MULTICENTER STUDY. Endoscopy 2021; 53: S68.



Publication History

Article published online:
19 March 2021

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