Effectiveness and Tolerability of Very Low Volume (Pleinvue) PreparatiÓn for Colonoscopy in the Elderly. Result Of a Prospective Study

Aims The use of colonoscopy in the elderly is increasing. However, the indication is debatable, in this population can prevent the morbidity and mortality of late colorectal cancer. Colonoscopy it has been considered challenging because of the difficulty in preparing this population.

Our study aims are to assess de effectiveness and tolerability of a low volume preparation (Pleinvue) in patients over 65 years old and evaluate the diagnostic yield of colonoscopic in them.

Methods 223 consecutive patients older than 65 years were collected, all patient receive a split dose preparatión, with a non-rsidue diet in the 48 previous hours and respecting the night break. They can drink clear liquids ad libitum. The Charlston and BBPS index was evaluated, and also the symptoms perceived by the patients during the preparatión and the diagnostic findings in the colonoscopy. All patients were also interviewed at least 48 hours after the procedure.

Results The median age was 73.7y. The median Charlston fragility index was 0.65. The BBPS was 7.96, and 62 % was classified as 9. Only 6.6 % of patients have a preparatión qualified as inadequate without difference between sexes. 95.5 % of patients report a good tolerance without any symptoms in 90.6 % to the first dose and 87.4 % to the second one. 3.6 % be nauseous, and 4.5 % had vomitos and a 0.9 % general discomfort without interference with the quality of the preparatión. The multivariate analysis don does not demonstrate any variable that affects significatively to bowel cleansing. The patients with a BBPS<4 have a higher Charlston index: 1.83 (p=0.005). The ADR was 43.9 % with 5.8 % of large resectable lessons and 0.9 of CRC. There are no perforations, adverse events nor non-programmed hospital income.

Conclusions In the elderly, a low volume split dose (Pleinvue) was well tolerated and resulted in good preparation and then followed by high efficacy colonoscopy.

Citation: Rodriguez Muñoz S, Esteban Fernandez-Zarza C Arberas Diez B etal. eP295 EFFECTIVENESS AND TOLERABILITY OF VERY LOW VOLUME (PLEINVUE) PREPARATIÓN FOR COLONOSCOPY IN THE ELDERLY. RESULT OF A PROSPECTIVE STUDY. Endoscopy 2021; 53: S195.

Publication History

Article published online:
19 March 2021