Diverticulosis And Colorectal Adenomas: Any Relationship?

Aims Colonic diverticulosis and colorectal adenomas share the same risk factors such as advanced age, physical inactivity, and western diet. Our study aimed at exploring the association between diverticulosis and colorectal adenomas.

Methods This is a cross-sectional study of patients who have had a colonoscopy. Two groups were identified: Group 1: Patients with diverticulum on colonoscopy and group 2: Patients without diverticulum on colonoscopy. Data about patient’s demographic characteristics, colonoscopy, polypectomy and pathological examination were collected. Patients with chronic inflammatory bowel disease, colorectal neoplasia, complicated colonic diverticulosis as well as those with incomplete or poorly prepared colonoscopy (Boston score < 7) were excluded.

Results A total of 114 patients were included 60 (52 %) patients=Group 1, 54 (48 %) patients=Group 2. Patient’s demographic and clinical features were comparable in both groups attested by: median age (63 y. vs. 59 y.; p=0.9), gender (sex ratio M/F=1.2 vs. 0.74; p=0.15), body mass index (27 kg/m² vs. 28 kg/m²; p=0.6) as well as for diabetes mellitus (37 % vs. 25 %; p= 0.27) and high blood pressure (39 % vs. 40 %; p=0.9). There was a higher prevalence of colorectal polyps (50 % vs. 30 %; p=0.04, OR =1.6; 95 % CI: 1-1.27) and adenomas (96 % vs. 77 %; p= 0.02, OR = 2; 95 % CI: 1-5) in the diverticular vs. non diverticula patients. However, no significant association between diverticulosis and high-grade dysplasia or carcinoma in situ was revealed.

Conclusions In our series, diverticulosis was significantly associated with a higher risk of polyps and adenomas, which is consistent with the results of Western populations.

Citation: Laabidi S, Ennaifer R, Kefi M etal. eP306 DIVERTICULOSIS AND COLORECTAL ADENOMAS: ANY RELATIONSHIP? Endoscopy 2021; 53: S199.

Publikationsverlauf

Artikel online veröffentlicht:
19. März 2021