Attenuation Correction on CZT Cameras for Myocardial Perfusion Imaging: Comparison between Supine and Prone Imaging versus Low-Dose CT-Corrected Supine Imaging

Ziel/Aim The study investigated whether in CZT myocardial perfusion imaging a supine plus a prone acquisition is comparable to a supine acquisition with a low-dose CT attenuation correction.

Methodik/Methods Thirty-four patients with an indication for myocardial perfusion imaging were studied with a CZT camera in supine and prone position followed. A low dose CT was acquired with a SPECT-CT camera. Three data sets were obtained and considered for further analysis: (1) supine CZT, (2) supine CZT with CTAC, and (3) supine CZT with additional prone. We compared radiopharmaceutical uptake with 17-segment polartomograms, SSS, SRS, SDS, total of ischemic and scarred segments, scan classification and clinical decision making.

Ergebnisse/Results SSS of supine/supine CTAC/supine-prone was 341/229/253, SRS 246/156/164, and SDS 104/88/96. Total ischemic segments were 65/67/65 and total scarred segments 96/62/69. The frequency of normal scans was highest for supine-prone (41 %), followed by supine CTAC and supine (35 %/24 %). Supine imaging indicated 23 % of patients to undergo invasive coronary angiography, both supine CTAC and supine-prone 18 %.

Schlussfolgerungen/Conclusions Additional prone imaging and CTAC correct for the amount and extend of myocardial scars. Both methods increase the frequency of normal scans and show a significant agreement in clinical decision making. Additional prone imaging can be regarded as a comparable alternative to a low-dose CT for AC.

Publication History

Article published online:
08 April 2021