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CC BY-NC-ND 4.0 · Journal of Clinical Interventional Radiology ISVIR 2021; 5(02): 091-098
DOI: 10.1055/s-0041-1730083
Original Article

Prostatic Artery Embolization: An Alternative Treatment for Benign Prostatic Hyperplasia

Autor*innen

  • James F. Pike

    1   University of South Carolina School of Medicine Greenville, Greenville, South Carolina, United States

  • William F. Abel

    1   University of South Carolina School of Medicine Greenville, Greenville, South Carolina, United States

  • Tyler B. Seckel

    1   University of South Carolina School of Medicine Greenville, Greenville, South Carolina, United States

  • Christine M.G. Schammel

    2   Pathology Associates, Greenville, South Carolina, United States

  • William Flanagan

    1   University of South Carolina School of Medicine Greenville, Greenville, South Carolina, United States
    3   Department of Surgery, Division of Urology, Prisma Health Upstate, Greenville, South Carolina, United States

  • A. Michael Devane

    1   University of South Carolina School of Medicine Greenville, Greenville, South Carolina, United States
    4   Department of Radiology, Interventional Radiology, Prisma Health Upstate, Greenville, South Carolina, United States
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Abstract

Purpose Prostatic artery embolization (PAE) has emerged as a minimally invasive alternative for patients with prostates >80 mL and has demonstrated lower morbidity rates. We sought to evaluate PAE at a single tertiary medical center. Methods A retrospective review of all patients who underwent PAE was completed. Demographic, clinicopathologic, procedure, and outcome data were collected to include international prostatic symptom score (IPSS) and quality of life (QoL) assessments. Results The pre-PAE mean prostate-specific antigen (PSA) was 8.4 ng/mL, mean prostate volume was 146.9 mL (9% >200 mL), and mean postvoid residual (PVR) was 208.2 mL (21.9% 200–300 mL). IPSS mean was 19.8 and QoL was “mostly dissatisfied.” Following PAE, mean PSA was reduced by 3.2 ng/mL (38.1%, p = 0.3014), the mean prostate volume reduction was 59.2 mL (40.3%, n = 19, p < 0.0001), and the average PVR reduction was 150.3 mL (72.2%, n = 27, p = 0.0002). Average IPSS score was also lower (11.9; 60.1%, n = 25, p < 0.0001) and QoL was reduced to “mostly satisfied” (p < 0.0001). Technical success was 100% with 24% minor morbidities. Conclusion PAE is a successful treatment for patients with BPH resulting in large prostates that are not good candidates for simple prostatectomy, providing optimal care with less operative and postoperative complications.

Keywords

prostatic artery embolization - benign prostatic hyperplasia - prostate volume >80 mL


Publikationsverlauf

Artikel online veröffentlicht:
30. Juni 2021

© 2021. Indian Society of Vascular and Interventional Radiology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

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