CC BY-NC-ND 4.0 · Journal of Clinical Interventional Radiology ISVIR 2021; 5(02): 123-126
DOI: 10.1055/s-0041-1730104
Case Report

Paradoxical Cerebral Embolism Secondary to Superior Vena Cava Occlusion and Development of a Systemic Right-to-Left Shunt

Ronny J.D. Kuang
1   Department of Radiology, Alfred Hospital, Melbourne, Victoria, Australia
,
2   Department of Medicine, Monash University, Melbourne, Victoria, Australia
3   Department of Cardiology, Alfred Hospital, Melbourne, Victoria, Australia
,
Jason E Bloom
2   Department of Medicine, Monash University, Melbourne, Victoria, Australia
3   Department of Cardiology, Alfred Hospital, Melbourne, Victoria, Australia
,
1   Department of Radiology, Alfred Hospital, Melbourne, Victoria, Australia
4   Department of Surgery, Monash University, Melbourne, Victoria, Australia
5   National Trauma Research Institute, Melbourne, Victoria, Australia
› Author Affiliations
Funding 
None declared.


Abstract

Paradoxical cerebral embolism, although rare, can be secondary to acquired causes such as superior vena cava (SVC) occlusion and development of a mediastinal right-to-left shunt. Such shunts allow undisturbed passage of thromboemboli to bypass the pulmonary circulation and enter the systemic circulation. This report presents a case of paradoxical cerebral embolism due to a right-to-left shunt originating from occlusion of the SVC. The etiology of the SVC occlusion stems from a prior central venous access line used for treatment of lymphoma. The patient underwent endovascular treatment with successful coil embolization of the mediastinal shunt.



Publication History

Article published online:
18 May 2021

© 2021. Indian Society of Vascular and Interventional Radiology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Wilson ES. Systemic to pulmonary venous communication in the superior vena caval syndrome. AJR Am J Roentgenol 1976; 127 (02) 247-249
  • 2 Cihangiroglu M, Lin BH, Dachman AH. Collateral pathways in superior vena caval obstruction as seen on CT. J Comput Assist Tomogr 2001; 25 (01) 1-8
  • 3 Madan AK, Allmon JC, Harding M, Cheng SS, Slakey DP. Dialysis access-induced superior vena cava syndrome. Am Surg 2002; 68 (10) 904-906
  • 4 Bashist B, Parisi A, Frager DH, Suster B. Abdominal CT findings when the superior vena cava, brachiocephalic vein, or subclavian vein is obstructed. AJR Am J Roentgenol 1996; 167 (06) 1457-1463
  • 5 Holemans JA, Howlett DC, Rankin SC. Case report: superior vena cava obstruction: unusual CT findings due to venous collaterals. ClinRadiol 1997; 52 (07) 559-560
  • 6 Nascimbene A, Angelini P. Superior vena cava thrombosis and paradoxical embolic stroke due to collateral drainage from the brachiocephalic vein to the left atrium. Tex Heart Inst J 2011; 38 (02) 170-173
  • 7 Muramatsu T, Miyamae T, Dohi Y. Collateral pathways observed by radionuclide superior cavography in 70 patients with superior vena caval obstruction. ClinNucl Med 1991; 16 (05) 332-336
  • 8 Avezbadalov A, Gutierrez C. Systemic-to-pulmonary venous shunt in a patient with non-Hodgkin lymphoma: a case report and review of the literature. Respir Med Case Rep 2015; 15: 9-11
  • 9 Forauer AR, Theoharis CG, Dasika NL. Jugular vein catheter placement: histologic features and development of catheter-related (fibrin) sheaths in a swine model. Radiology 2006; 240 (02) 427-434
  • 10 Geerts W. Central venous catheter-related thrombosis. Hematology (Am SocHematolEduc Program) 2014; 2014 (01) 306-311
  • 11 Grayet D, Ghaye B, Szapiro D, Dondelinger RF. Systemic-to-pulmonary venous shunt in superior vena cava obstruction revealed on dynamic helical CT. AJR Am J Roentgenol 2001; 176 (01) 211-213
  • 12 Kapur S, Paik E, Rezaei A, Vu DN. Where there is blood, there is a way: unusual collateral vessels in superior and inferior vena cava obstruction. Radiographics 2010; 30 (01) 67-78