Am J Perinatol 2023; 40(07): 793-798
DOI: 10.1055/s-0041-1731279
Original Article

Can Mozart Improve Weight Gain and Development of Feeding Skills in Premature Infants? A Randomized Trial

1   Department of Pediatrics, Christiana Care Health System, Newark, Delaware
2   Department of Pediatrics, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania
,
Amy Mackley
1   Department of Pediatrics, Christiana Care Health System, Newark, Delaware
,
Pam Green
1   Department of Pediatrics, Christiana Care Health System, Newark, Delaware
,
Deborah Ottenthal
1   Department of Pediatrics, Christiana Care Health System, Newark, Delaware
,
Robert Locke
1   Department of Pediatrics, Christiana Care Health System, Newark, Delaware
2   Department of Pediatrics, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania
,
Ursula Guillen
1   Department of Pediatrics, Christiana Care Health System, Newark, Delaware
2   Department of Pediatrics, Sidney Kimmel Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania
› Institutsangaben
Funding None.

Abstract

Objective The study aimed to assess in a prospective randomized study the effect of Mozart's music on time to regain birth weight (BW) and development of oral feeding skills in babies born between 280/7 and 316/7 weeks of gestation.

Study Design Healthy premature infants born between 280/7 and 316/7 completed weeks of gestation were randomized within 3 days of birth to either music or no music exposure. Infants in the music group were exposed to Mozart's double piano sonata twice per day for 14 days. The primary outcome was time to regain birth weight. The secondary outcome was development of oral feeding skills as evaluated by a speech/language pathologist blinded to the intervention. We hypothesized that exposure to Mozart's double piano sonata would decrease time to regain BW and improve feeding skills. A total of 32 newborns were needed to detect a 3-day difference in time to regain BW.

Results Forty infants were enrolled and randomized. There were no significant differences between the two groups regarding the time to regain BW (p = 0.181) and the time to achievement of full oral feeds (p = 0.809).

Conclusion Exposure to Mozart's double piano sonata for 14 days after birth did not significantly improve time to regain BW or time to achieve full oral feedings in very premature infants. It is possible that Mozart's music has no effect or that the duration of music exposure was not sufficient to have a physiologic effect on growth and oral feeding skills.

Key Points

  • Classical music improves the medical condition of adults.

  • Music decreases neonatal resting energy expenditure.

  • Music exposure did not significantly impact weight gain.

  • This clinical relevance warrants further evaluation.

Note

Parental consent was required and obtained for all patients in this study.




Publikationsverlauf

Eingereicht: 14. Januar 2021

Angenommen: 12. Mai 2021

Artikel online veröffentlicht:
22. Juni 2021

© 2021. Thieme. All rights reserved.

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  • References

  • 1 Rauscher FH, Shaw GL, Ky KN. Music and spatial task performance. Nature 1993; 365 (6447): 611
  • 2 Lubetzky R, Mimouni FB, Dollberg S, Reifen R, Ashbel G, Mandel D. Effect of music by Mozart on energy expenditure in growing preterm infants. Pediatrics 2010; 125 (01) e24-e28
  • 3 Loewy J, Stewart K, Dassler AM, Telsey A, Homel P. The effects of music therapy on vital signs, feeding, and sleep in premature infants. Pediatrics 2013; 131 (05) 902-918
  • 4 Caparros-Gonzalez RA, de la Torre-Luque A, Diaz-Piedra C, Vico FJ, Buela-Casal G. Listening to relaxing music improves physiological responses in premature infants: a randomized controlled trial. Adv Neonatal Care 2018; 18 (01) 58-69
  • 5 American Academy of Pediatrics Committee on Nutrition. American Academy of Pediatrics Committee on Nutrition: Nutritional needs of low-birth-weight infants. Pediatrics 1985; 75 (05) 976-986
  • 6 American Academy of Pediatrics. Committee on Environmental Health. Noise: a hazard for the fetus and newborn. Pediatrics 1997; 100 (04) 724-727
  • 7 Waitzman KA, Ludwig SM, Nelson CL. Contributing to content validity of the infant-driven feeding scales through Delphi Surveys. Newborn Infant Nurs Rev 2014; 14: 88-91
  • 8 Jenkins JS. The Mozart effect. J R Soc Med 2001; 94 (04) 170-172
  • 9 Rauscher FH, Robinson KD, Jens JJ. Improved maze learning through early music exposure in rats. Neurol Res 1998; 20 (05) 427-432
  • 10 Hughes JR. The Mozart effect. Epilepsy Behav 2001; 2 (05) 396-417
  • 11 Hughes JR. The Mozart effect: additional data. Epilepsy Behav 2002; 3 (02) 182-184
  • 12 White JM. Effects of relaxing music on cardiac autonomic balance and anxiety after acute myocardial infarction. Am J Crit Care 1999; 8 (04) 220-230
  • 13 Hartling L, Shaik MS, Tjosvold L, Leicht R, Liang Y, Kumar M. Music for medical indications in the neonatal period: a systematic review of randomised controlled trials. Arch Dis Child Fetal Neonatal Ed 2009; 94 (05) F349-F354
  • 14 Loewy J, Jaschke AC. Mechanisms of Timing, Timbre, Repertoire, and Entrainment in Neuroplasticity: Mutual Interplay in Neonatal Development. Front Integr Neurosci 2020;14(08):
  • 15 Chorna OD, Slaughter JC, Wang L, Stark AR, Maitre NL. A pacifier-activated music player with mother's voice improves oral feeding in preterm infants. Pediatrics 2014; 133 (03) 462-468