RSS-Feed abonnieren
PDF herunterladen
DOI: 10.1055/s-0041-1732849
Angiogenesis in Cancer
Autor*innen
Introduction
It took two centuries to describe the role of angiogenesis inhibitors in tumor shrinkage by Judah Folkman, after the term angiogenesis was initially coined by John Hunter. Even later, the vascular endothelial growth factor (VEGF) was discovered by Napoleon Ferrara. This concept of angiogenesis has revolutionized the field of oncology in better understanding the mechanism of cancer progression, resulting in the development of numerous targeted therapies for cancer treatment. Hence, in 2000, Hanahan and Weinberg rightly enumerated the induction of angiogenesis as one of the hallmarks of cancer.
Publikationsverlauf
Artikel online veröffentlicht:
05. August 2021
© 2021. Indian Society of Medical and Paediatric Oncology. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial-License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Thieme Medical and Scientific Publishers Private Ltd.
A-12, Second Floor, Sector -2, NOIDA -201301, India
-
References
- 1 Lugano R, Ramachandran M, Dimberg A. Tumor angiogenesis: causes, consequences, challenges and opportunities. Cell Mol Life Sci 2020; 77 (09) 1745-1770
- 2 Hida K, Ohga N, Hida Y, Shindoh M. Significance of anti-angiogenic therapy in head and neck cancer—heterogeneity of tumor endothelium. Jpn Dent Sci Rev 2010; 46 (01) 26-32
- 3 Amin A, Hammers H. The evolving landscape of immunotherapy-based combinations for frontline treatment of advanced renal cell carcinoma. Front Immunol 2019; 9: 3120
- 4 Prager GW, Poettler M, Unseld M, Zielinski CC. Angiogenesis in cancer: anti-VEGF escape mechanisms. Transl Lung Cancer Res 2012; 1 (01) 14-25