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CC BY-NC-ND 4.0 · AJP Rep 2021; 11(03): e123-e126
DOI: 10.1055/s-0041-1735633
Case Report

Newborn Septic Arthritis—A Rare Presentation of Late-Onset Group B Streptococcal Disease: Case Report and Short Review of the Literature

Rahel Schuler
1   Department of General Pediatrics and Neonatology, Justus Liebig University, Giessen, Germany
,
Harald Ehrhardt
1   Department of General Pediatrics and Neonatology, Justus Liebig University, Giessen, Germany
,
Klaus-Peter Zimmer
1   Department of General Pediatrics and Neonatology, Justus Liebig University, Giessen, Germany
,
Daniel Berthold
2   Department of Diagnostic and Interventional Radiology, University Hospital Giessen, Justus Liebig University, Giessen, Germany
,
Janina Trauth
3   Department of Medicine II, Section of Infectious Diseases, Justus Liebig University, Giessen, Germany
,
Christian Fölsch
4   Department of Orthopaedic Surgery, Justus-Liebig-University, Giessen, Germany
,
Markus Waitz
1   Department of General Pediatrics and Neonatology, Justus Liebig University, Giessen, Germany
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Abstract

Group B Streptococcus (GBS) disease is a leading cause of invasive bacterial infections among neonates. We present the case of an 11-day-old neonate with septic arthritis as a rare presentation of late-onset disease (LOD) with a favorable short-term outcome. GBS is a leading cause of neonatal infection. Early-onset disease (EOD) is defined as infection from birth to 6 days of age, while LOD occurs from 7 days to approximately 3 months of age. EOD is acquired through vertical transmission and can be reduced through application of intrapartum antibiotic prophylaxis (IAP). LOD can be acquired from the mother or from environmental sources, unlikely to be prevented by IAP. The most common presentation of EOD is bacteremia (83%), pneumonia (9%), and meningitis (7%). While the clinical picture in both EOD and LOD frequently resembles in LOD hamatogenous spreading may predispose neonates to present with uncommon organ manifestation other than the classic systemic signs of sepsis, for example, septic arthritis. Herein, we report on the management and outcome of a term neonate with late onset GqBS bacteremia and subtle clinical symptoms of septic monoarthritis.

Keywords

septic arthritis - newborn - late-onset sepsis - group B Streptococcus disease


Publication History

Received: 13 April 2021

Accepted: 10 May 2021

Article published online:
30 September 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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