Application of 5% Lidocaine Adhesive Patch in Painful Surgical Scars: Clinical Trial^[*]

Abstract

Objective The present paper aims to evaluate the use of a 5% lidocaine patch to treat neuropathic pain after orthopedic procedures in comparison with therapeutic massage over surgical incisions.

Methods This is a prospective, randomized clinical trial with 37 patients who underwent orthopedic surgery from January 2015 to February 2017. The study included subjects aged 13 to 70 years old who underwent foot and ankle orthopedic surgery and presented neuropathic pain or hypersensitivity at the surgical incision site for at least 90 days after the procedure. All patients were assessed for pain (using the visual analog scale [VAS]) and quality of life (with the SF-36 questionnaire) at the beginning of the treatment and after 30, 60, and 90 days.

Results Although the treatment improved pain in both groups, subjects using the lidocaine patch presented greater pain reduction over time. There were no statistically significant differences in the SF-36 questionnaire, with no significant evidence regarding functional capacity, physical aspects, vitality, emotional aspects, social aspects, general health condition, and mental health. The great advantage of the patch was the degree of personal satisfaction of the patients, with statistical relevance, probably due to the easy application and psychological effect of a drug therapy.

Conclusion Lidocaine patches and massages are effective treatment methods for reducing scar tissue pain, with similar outcomes. The patches improved the degree of patient satisfaction. Level of Evidence 1. Prospective randomized clinical trial.

Keywords

orthopedic procedures - pain - neuralgia - lidocaine - massage

^* Study performed at the Orthopedics and Traumatology Service, Hospital Ipiranga, São Paulo, SP, Brazil.

Authors' Contribution

Each author contributed individually and significantly to the development of the present article. Macedo R. R. (0000-0002-2563-2085)*, Santos J. P. G. (0000-0002-1086-9872)*, Lobato E. S. (0000-0002-7181-6133)* and Mendes Júnior J. P. (0000-0003-1514-5029)* were the main collaborators for manuscript preparation. Santos J. P. G. (0000-0002-1086-9872)*, Lobato E. S. (0000-0002-7181-6133)* and Mendes Júnior J. P. (0000-0003-1514-5029)* performed the follow-up of the patients and collected clinical data. Santos J. P. G. (0000-0002-1086-9872)*, Lobato E. S. (0000-0002-7181-6133)* and Mendes Júnior J. P. (0000-0003-1514-5029)* evaluated the data for statistical analysis. Macedo R. R. (0000-0002-2563-2085)*, Santos J. P. G. (0000-0002-1086-9872)*, Lobato E. S. (0000-0002-7181-6133)* and Mendes Júnior J. P. (0000-0003-1514-5029)* conducted the literature review. Ikemoto R. Y. (0000-0001-7718-1186)* and Rodrigues L. M. R. (0000-0001-6891-5395)* reviewed the manuscript and contributed to the intellectual concept of the study. *ORCID (Open Researcher and Contributor ID).

Publication History

Received: 05 October 2020

Accepted: 08 March 2021

Article published online:
28 October 2021

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