CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2021; 31(04): 858-866
DOI: 10.1055/s-0041-1735928
Original Article

Technical and Medium-Term Clinical Outcomes of Transjugular Intrahepatic Portosystemic Shunt with Fluoroscopy and Additional Trans-abdominal Ultrasound Guidance

1   Department of Interventional Radiology, Christian Medical College, Vellore, Tamil Nadu, India
,
1   Department of Interventional Radiology, Christian Medical College, Vellore, Tamil Nadu, India
,
2   Department of Hepatology, Christian Medical College, Vellore, Tamil Nadu, India
,
1   Department of Interventional Radiology, Christian Medical College, Vellore, Tamil Nadu, India
,
1   Department of Interventional Radiology, Christian Medical College, Vellore, Tamil Nadu, India
,
1   Department of Interventional Radiology, Christian Medical College, Vellore, Tamil Nadu, India
,
2   Department of Hepatology, Christian Medical College, Vellore, Tamil Nadu, India
,
2   Department of Hepatology, Christian Medical College, Vellore, Tamil Nadu, India
,
2   Department of Hepatology, Christian Medical College, Vellore, Tamil Nadu, India
› Author Affiliations
Funding None.

Abstract

Background and Objective The aim of the study is to evaluate the technical and clinical outcomes of transjugular intrahepatic portosystemic shunt (TIPS) performed with additional transabdominal ultrasound guidance.

Material and Methods Patients who underwent TIPS between January 2004 to January 2020 in our center were studied. Technical, hemodynamic, angiographic, and clinical outcome were recorded up to 1 year of follow-up.

Results TIPS was attempted in 162 patients (median [range] age 37[3–69] years; 105 were males and 57 were females; Etiology: Budd-Chiari syndrome [BCS] 91, cirrhosis 65, symptomatic acute portal venous thrombosis [PVT] 3, veno-occlusive disease [VOD] 2, congenital portosystemic shunt [CPSS] 1) during the study period. Indication for TIPS was refractory ascites in 135 patients (BCS 86, cirrhosis 49) and variceal bleed in 21 patients (BCS 5, cirrhosis 16). Technical success was seen in 161 of the 162 (99.4%) patients. The tract was created from hepatic vein in 55 patients and inferior vena cava (IVC) in 106 patients. Complications within 1 week post TIPS were seen in 29 of the 162 (18%) patients, of whom one developed unexplained arrhythmia and hypotension and died. Of the patients with available follow-up, clinical success was noted in 120 (81%), while 14 (9%) patients had partial nonresponse and six (4%) had complete nonresponse. Eight (5%) patients died during the follow-up period.

Conclusion The technical success of TIPS creation with additional transabdominal ultrasound guidance is very high with low peri-procedural complication rate. It has enabled the inclusion of a wider spectrum of cases like acute PVT and obliterated hepatic veins which were otherwise considered contraindications.

Ethical Approval

Obtained.




Publication History

Article published online:
30 November 2021

© 2021. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Medical and Scientific Publishers Pvt. Ltd.
A-12, 2nd Floor, Sector 2, Noida-201301 UP, India

 
  • References

  • 1 Richter GM, Palmaz JC, Nöldge G. et al. The transjugular intrahepatic portosystemic stent-shunt. A new nonsurgical percutaneous method. Radiologe 1989; 29 (08) 406-411
  • 2 Farsad K, Kaufman JA. Novel image guidance techniques for portal vein targeting during transjugular intrahepatic portosystemic shunt creation. Tech Vasc Interv Radiol 2016; 19 (01) 10-20
  • 3 Keshava SN, Kota GK, Mammen T. et al. Direct intrahepatic cavo-portal shunts in Budd-Chiari syndrome: role of simultaneous fluoroscopy and trans-abdominal ultrasonography. Indian J Gastroenterol 2006; 25 (05) 248-250
  • 4 Escorsell À, Pavel O, Cárdenas A. et al; Variceal Bleeding Study Group. Esophageal balloon tamponade versus esophageal stent in controlling acute refractory variceal bleeding: a multicenter randomized, controlled trial. Hepatology 2016; 63 (06) 1957-1967
  • 5 European Association for the Study of the Liver. Electronic address: easloffice@easloffice.eu, European Association for the Study of the Liver. EASL clinical practice guidelines for the management of patients with decompensated cirrhosis. J Hepatol 2018; 69 (02) 406-460
  • 6 Asrani SK, Kim WR. Model for end-stage liver disease: end of the first decade. Clin Liver Dis 2011; 15 (04) 685-698
  • 7 Garcia-Pagán JC, Heydtmann M, Raffa S. et al; Budd-Chiari Syndrome-Transjugular Intrahepatic Portosystemic Shunt Group. TIPS for Budd-Chiari syndrome: long-term results and prognostics factors in 124 patients. Gastroenterology 2008; 135 (03) 808-815
  • 8 Surendrababu NR, Keshava SN, Eapen CE, Zachariah UG. Transjugular intrahepatic portocaval shunt placed through the strut of an inferior vena cava stent in a patient with Budd-Chiari syndrome: a technical modification. Br J Radiol 2010; 83 (985) e22-e24
  • 9 Ahmed M, Keshava SN, Moses V. et al. Transjugular intrahepatic portosystemic shunt through the strut of a previously placed stent: technical feasibility and long-term follow-up results. Cardiovasc Intervent Radiol 2018; 41 (11) 1794-1798
  • 10 Mammen S, Keshava SN, Kattiparambil S. Acute portal vein thrombosis, no longer a contraindication for transjugular intrahepatic porto-systemic shunt (TIPS) insertion. J Clin Exp Hepatol 2015; 5 (03) 259-261
  • 11 Fanelli F. The evolution of transjugular intrahepatic portosystemic shunt: tips. ISRN Hepatol 2014; 2014: 762096
  • 12 Rössle M, Siegerstetter V, Olschewski M, Ochs A, Berger E, Haag K. How much reduction in portal pressure is necessary to prevent variceal rebleeding? A longitudinal study in 225 patients with transjugular intrahepatic portosystemic shunts. Am J Gastroenterol 2001; 96 (12) 3379-3383
  • 13 Beathard GA, Urbanes A, Litchfield T. The classification of procedure-related complications—a fresh approach. Semin Dial 2006; 19 (06) 527-534
  • 14 Semba CP, Saperstein L, Nyman U, Dake MD. Hepatic laceration from wedged venography performed before transjugular intrahepatic portosystemic shunt placement. J Vasc Interv Radiol 1996; 7 (01) 143-146
  • 15 Livingstone RS, Keshava SN. Technical note: reduction of radiation dose using ultrasound guidance during transjugular intrahepatic portosystemic shunt procedure. Indian J Radiol Imaging 2011; 21 (01) 13-14
  • 16 Farsad K, Fuss C, Kolbeck KJ. et al. Transjugular intrahepatic portosystemic shunt creation using intravascular ultrasound guidance. J Vasc Interv Radiol 2012; 23 (12) 1594-1602
  • 17 Hodgson JM, Graham SP, Savakus AD. et al. Clinical percutaneous imaging of coronary anatomy using an over-the-wire ultrasound catheter system. Int J Card Imaging 1989; 4 (2-4): 187-193
  • 18 Zabicki B, Ricke J, Dudeck O, Pech M. CT-assisted transfemoral intrahepatic portosystemic shunt in a long duration follow-up: a case report. Pol J Radiol 2014; 79: 39-41
  • 19 Quinn SF, Sheley RC, Semonsen KG. Creation of a portal vein to inferior vena cava shunt using CT guidance and a covered endovascular stent. AJR Am J Roentgenol 1997; 169 (04) 1159-1160
  • 20 Kee ST, Ganguly A, Daniel BL. et al. MR-guided transjugular intrahepatic portosystemic shunt creation with use of a hybrid radiography/MR system. J Vasc Interv Radiol 2005; 16 (2 Pt 1): 227-234
  • 21 Qi X, Han G. Transjugular intrahepatic portosystemic shunt in the treatment of portal vein thrombosis: a critical review of literature. Hepatol Int 2012; 6 (03) 576-590
  • 22 Fidelman N, Kwan SW, LaBerge JM, Gordon RL, Ring EJ, Kerlan Jr RK. The transjugular intrahepatic portosystemic shunt: an update. AJR Am J Roentgenol 2012; 199 (04) 746-755
  • 23 Deibert P, Schwarz S, Olschewski M, Siegerstetter V, Blum HE, Rössle M. Risk factors and prevention of early infection after implantation or revision of transjugular intrahepatic portosystemic shunts: results of a randomized study. Dig Dis Sci 1998; 43 (08) 1708-1713
  • 24 Cura M, Cura A, Suri R, El-Merhi F, Lopera J, Kroma G. Causes of TIPS dysfunction. AJR Am J Roentgenol 2008; 191 (06) 1751-1757
  • 25 Garcia-Tsao G, Parikh CR, Viola A. Acute kidney injury in cirrhosis. Hepatology 2008; 48 (06) 2064-2077
  • 26 Zheng M, Chen Y, Bai J. et al. Transjugular intrahepatic portosystemic shunt versus endoscopic therapy in the secondary prophylaxis of variceal rebleeding in cirrhotic patients: meta-analysis update. J Clin Gastroenterol 2008; 42 (05) 507-516
  • 27 Popovic P, Stabuc B, Skok P, Surlan M. Transjugular intrahepatic portosystemic shunt versus endoscopic sclerotherapy in the elective treatment of recurrent variceal bleeding. J Int Med Res 2010; 38 (03) 1121-1133
  • 28 Pleguezuelo M, Benitez JM, Jurado J, Montero JL, De la Mata M. Diagnosis and management of bacterial infections in decompensated cirrhosis. World J Hepatol 2013; 5 (01) 16-25
  • 29 Smith MT, Rase B, Woods A. et al. Risk of hernia incarceration following transjugular intrahepatic portosystemic shunt placement. J Vasc Interv Radiol 2014; 25 (01) 58-62
  • 30 Trotter JF, Suhocki PV. Incarceration of umbilical hernia following transjugular intrahepatic portosystemic shunt for the treatment of ascites. Liver Transpl Surg 1999; 5 (03) 209-210
  • 31 Boyer TD, Haskal ZJ. American Association for the Study of Liver Diseases. The role of transjugular intrahepatic portosystemic shunt in the management of portal hypertension. Hepatology 2005; 41 (02) 386-400
  • 32 Boyer TD, Haskal ZJ. American Association for the Study of Liver Diseases. The role of transjugular intrahepatic portosystemic shunt (TIPS) in the management of portal hypertension: update 2009. Hepatology 2010; 51 (01) 306
  • 33 Qi X, Han G, Yin Z. et al. Transjugular intrahepatic portosystemic shunt for portal cavernoma with symptomatic portal hypertension in non-cirrhotic patients. Dig Dis Sci 2012; 57 (04) 1072-1082
  • 34 Sharma A, Keshava SN, Eapen A, Elias E, Eapen CE. An update on the management of Budd-Chiari syndrome. Dig Dis Sci 2021; 66 (06) 1780-1790
  • 35 Ahmed M, Keshava SN. Interventions for portal hypertension: trans jugular intrahepatic portosystemic shunts (TIPS). In: Mukund A. ed. Basics of Hepatobiliary Interventions. 1st ed.. Singapore: Springer; 2021: 187-200