CC BY 4.0 · Journal of Child Science 2021; 11(01): e287-e295
DOI: 10.1055/s-0041-1736478
Original Article

Study on Inborn and Outborn Neonatal Admissions in Relation to Gestational Maturity in Neonatal Intensive Care Unit at a Tertiary Care University Hospital in Upper Egypt

1   Department of Paediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt
,
2   Department of Medical Physiology, Faculty of Medicine, Assiut University, Assiut, Egypt
,
1   Department of Paediatrics, Faculty of Medicine, Assiut University, Assiut, Egypt
› Author Affiliations
Funding None

Abstract

Neonatal morbidity and mortality rates indicate a country's socioeconomic status and the quality, and effectiveness of its health care system. This research aimed to identify the clinical pattern and causes of neonatal admission for inborn and outborn babies in a tertiary care university hospital and their outcomes. Over a year, this prospective hospital-based research was conducted in the neonatal intensive care unit (NICU) of Assiut Children's Hospital in Upper Egypt (January 1st to December 31st, 2020). Gender, birth weight, gestational age, postnatal age, delivery mode, delivery place, admission cause, hospital stay period, and neonatal outcomes were collected. A total of 1,638 newborns were admitted; 930 (56.8%) were preterm and 708 (43.2%) full-term. Inborn admissions were 1,056 (64.5%) and outborn 582 (35.5%). The majority of inborn admissions were preterm 726 (68.8%), and outborn were full-term 378 (64.9%). The commonest admission causes among inborn and outborn preterm infants were respiratory distress syndrome (84.3%) and congenital intestinal obstruction (22.5%), respectively, while multiple congenital anomalies were the commonest cause for admission among both inborn and outborn full-term babies. The mortality rate was 708 (43.2%), higher among inborn (50%) versus outborn (30.9%). The leading cause of death was respiratory distress syndrome among premature inborn with case fatality rate of (56.9%) and multiple congenital anomalies among premature outborn (60%), as well as inborn (67.4%), and outborn (42.6%) full-term neonates. In conclusion, the neonatal mortality rate was high among studied cases. Morbidity and mortality of respiratory distress syndrome and congenital anomalies were alarmingly high. Therefore, all health care providers must devote a considerable effort to improve health care delivered to these neonates.

Authors' Contribution

S.M.A.-A. carried the study design, examined cases, and shared in the writing of manuscript. E.A.H. was involved in the selection of cases, data collection and entry, validation, and coding, as well as shared in writing the manuscript. A.M. S. was involved in selection of cases, data collection, and shared in writing the manuscript and gathering references. All authors have read and approved the manuscript for publication.




Publication History

Received: 21 May 2021

Accepted: 30 August 2021

Article published online:
22 November 2021

© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

Georg Thieme Verlag KG
Rüdigerstraße 14, 70469 Stuttgart, Germany

 
  • References

  • 1 Parasher V, Khatri R, Yadav S, Mittal U. The pattern of admission and their related outcomes in NICU of a tertiary care teaching hospital, Udaipur, Rajasthan, India. Pediatr Rev-Int J Pediatr Res 2021; 8 (01) 16-22
  • 2 Hug L, Alexander M, You D, Alkema L. UN Inter-agency Group for Child Mortality Estimation. National, regional, and global levels and trends in neonatal mortality between 1990 and 2017, with scenario-based projections to 2030: a systematic analysis. Lancet Glob Health 2019; 7 (06) e710-e720
  • 3 King BC, Mowitz ME, Zupancic JAF. The financial burden on families of infants requiring neonatal intensive care. Semin Perinatol 2021; 45 (03) 151394
  • 4 Belachew A, Tewabe T, Dessie G. Neonatal mortality and its association with antenatal care visits among live births in Ethiopia: a systematic review and meta-analysis. J Matern Fetal Neonatal Med 2020; 26: 1-8 DOI: 10.1080/14767058.2020.1718093.
  • 5 Wardlaw T, You D, Hug L, Amouzou A, Newby H. UNICEF Report: enormous progress in child survival but greater focus on newborns urgently needed. Reprod Health 2014; 11 (01) 82
  • 6 Organization WH. World Health Statistics 2019: Monitoring Health for the SDGs, Sustainable Development Goals. 2019
  • 7 Organization WH. Every Newborn: An Action Plan to End Preventable Deaths. 2014
  • 8 Bishop D, Dyer RA, Maswime S. et al; ASOS investigators. Maternal and neonatal outcomes after caesarean delivery in the African Surgical Outcomes Study: a 7-day prospective observational cohort study. Lancet Glob Health 2019; 7 (04) e513-e522
  • 9 Muhe LM, McClure EM, Mekasha A. et al. A prospective study of causes of illness and death in preterm infants in Ethiopia: the SIP study protocol. Reprod Health 2018; 15 (01) 116
  • 10 Falciglia HS, Merkel RC, Glover V, Hasselfeld KA, Brady WK. The mortality of periviable and extremely premature infants and their impact on the overall neonatal mortality rate. Sci Rep 2020; 10 (01) 2503
  • 11 Abd El Aziz T, Elbanna E, Sarhan D, Ibrahim SE. Clinical characterizations of neonatal admission in neonatal intensive care unit at Zagazig University Children Hospital. Zagazig Univ Med J 2020; 26 (05) 775-786
  • 12 Fahmy N, Ramy N, El Houchi S. et al. Outborns or inborns: clinical audit of the two intensive care units of Cairo University Hospital. Egyptian Pediatric Association Gazette. 2017; 65 (01) 10-14
  • 13 Tekleab AM, Amaru GM, Tefera YA. Reasons for admission and neonatal outcome in the neonatal care unit of a tertiary care hospital in Addis Ababa: a prospective study. Res Rep Neonatol 2016; 6: 17-23
  • 14 El-Zanati F. Egypt Health Issues Survey, Ministry of Health and Population, El-Zanaty and Associates and, ICF International. International Central Agency for Public Mobilisation and Statistics Report issued by: Economic and Social Justice Unit: Knowledge and Prevalence of Hepatitis B and C. 2015: 25-50
  • 15 Bokade CM, Meshram RM. Morbidity and mortality patterns among outborn referral neonates in central India: Prospective observational study. J Clin Neonatol 2018; 7 (03) 130-135
  • 16 Verma J, Anand S, Kapoor N, Gedam S, Patel U. Neonatal outcome in newborns admitted in NICU of tertiary care hospital in central India: a 5-year study. Int J Contemp Pediatrics 2018; 5 (04) 1364-1367
  • 17 Ochoga M, Abah R, Michael A. et al. Retrospective assessment of neonatal morbidity and mortality in the special care baby unit of a private health facility in Benue State, North Central Nigeria. Niger J Paediatr 2020; 47 (04) 353-357
  • 18 Ekwochi U, Ndu IK, Nwokoye IC, Ezenwosu OU, Amadi OF, Osuorah D. Pattern of morbidity and mortality of newborns admitted into the sick and special care baby unit of Enugu State University Teaching Hospital, Enugu state. Niger J Clin Pract 2014; 17 (03) 346-351
  • 19 Seboka J, Abera AM, Rebitu AD. Pattern of admission and outcome of neonate admitted to Adama Hospital Medical College Neonatal Intensive Care Unit, Adama, Ethiopia. Int J Sci Basic Appl Res 2018; 42 (01) 59-71
  • 20 Ike Elizabeth U, Modupe OO. Pattern of diseases and care outcomes of neonates admitted in special care baby unit of University College Hospital, Ibadan, Nigeria from 2007 to 2011. J Nurs Health Sci 2015; 4 (01) 62-71
  • 21 Baseer KAA, Mohamed M, Abd-Elmawgood EA. Risk factors of respiratory diseases among neonates in neonatal intensive care unit of Qena University Hospital, Egypt. Ann Glob Health 2020; 86 (01) 22
  • 22 Elizabeth U, Oyetunde M. Pattern of diseases and care outcomes of neonates admitted in IOSR. J Nurs Heal Sci Ver I. 2015; 4: 1940-2320
  • 23 Eze P, Al-Maktari F, Alshehari AH, Lawani LO. Morbidities & outcomes of a neonatal intensive care unit in a complex humanitarian conflict setting, Hajjah Yemen: 2017-2018. Confl Health 2020; 14 (01) 53
  • 24 Aijaz N, Huda N, Kausar S. Disease burden of NICU, at a tertiary care hospital, Karachi. J Dow Univ Health Sci 2012; 6 (01) 32-35
  • 25 Hady S, Haie O, Eldesouky R, Gabal M. Incidence and the underlying factors of neonatal mortality in the university hospital of Benha, Egypt. Int J Med Health Sci 2016; 5 (04) 237-244
  • 26 El-Ganainy HFR, El-Mashad AE-RM, Shihab NS, Abu-Hamama AM. Risk factors for neonatal mortality in neonatal intensive care units in Tanta City. Egypt J Hosp Med 2019; 75 (01) 1996-2006
  • 27 Omoigberale AI, Sadoh WE, Nwaneri DU. A 4 year review of neonatal outcome at the University of Benin Teaching Hospital, Benin City. Niger J Clin Pract 2010; 13 (03) 321-325
  • 28 Raikwar P. A study of neonatal admission pattern and outcome from rural Haryana. Glob J Res Anal 2018; 19: 12-16
  • 29 Muthukumaran N. Mortality profile of neonatal deaths and deaths due to neonatal sepsis in a tertiary care center in southern India: a retrospective study. Int J Contemp Pediatrics 2018; 5 (04) 1583-1587
  • 30 Medhat H, Khashana A. Incidence of neonatal infection in South Sinai, Egypt. Int J Infect 2017; 4 (01) e36615
  • 31 Andegiorgish AK, Andemariam M, Temesghen S, Ogbai L, Ogbe Z, Zeng L. Neonatal mortality and associated factors in the specialized neonatal care unit Asmara, Eritrea. BMC Public Health 2020; 20 (01) 10
  • 32 Wang C, Zhou YH, Yang HX, Poon LC. Intrauterine vertical transmission of SARS-CoV-2: what we know so far. Ultrasound Obstet Gynecol 2020; 55 (06) 724-725