Osteologie 2021; 30(04): 341
DOI: 10.1055/s-0041-1736729
Abstract

Platelet-rich plasma factors enhance bone marrow stromal cell motility and survival by activating AKT signaling

M Stoeckl
1   IZKF Research Group Tissue Regeneration in Musculoskeletal Diseases, University Clinics Würzburg
2   Orthopedic Center for Musculoskeletal Research, University of Würzburg
,
D Trivanovic
1   IZKF Research Group Tissue Regeneration in Musculoskeletal Diseases, University Clinics Würzburg
2   Orthopedic Center for Musculoskeletal Research, University of Würzburg
,
B Schlierf
1   IZKF Research Group Tissue Regeneration in Musculoskeletal Diseases, University Clinics Würzburg
2   Orthopedic Center for Musculoskeletal Research, University of Würzburg
,
T Kreuzahler
1   IZKF Research Group Tissue Regeneration in Musculoskeletal Diseases, University Clinics Würzburg
2   Orthopedic Center for Musculoskeletal Research, University of Würzburg
,
M Rudert
2   Orthopedic Center for Musculoskeletal Research, University of Würzburg
3   Chair for Orthopedics, University of Würzburg
,
M Herrmann
1   IZKF Research Group Tissue Regeneration in Musculoskeletal Diseases, University Clinics Würzburg
2   Orthopedic Center for Musculoskeletal Research, University of Würzburg
› Author Affiliations
 

Introduction

Early phase of bone healing is coupled with hematoma formation which precedes regenerative processes. To investigate hematoma components, we explored the effects of platelet-rich plasma (PRP)-derived factors on MSC survival and motility.



Publication History

Article published online:
04 November 2021

© 2021. Thieme. All rights reserved.

Georg Thieme Verlag
Rüdigerstraße 14, 70469 Stuttgart, Germany