Abstract
Pituitary carcinoma is a rare disease with surgical, radiotherapeutic, and chemotherapeutic
treatment options. We present the case of a female patient diagnosed with a nonfunctioning
pituitary adenoma who underwent several surgical procedures, radiations, and chemotherapeutic
treatments with various substances. Sixteen years after the first diagnosis, a cranial
and spinal metastatic spread of the tumor occurred. We opted for an individual therapy
based on anecdotal evidence. Unfortunately, the recommended off-label treatment with
a somatostatin analog substance was never given due to bureaucratic delays. This case
report is about the challenging aspects of individual decision-making in rare neurosurgical
diseases.
Keywords
pituitary carcinoma - cranial and spinal metastasis - temozolomide - pasireotide