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CC BY 4.0 · Rev Bras Ginecol Obstet 2021; 43(10): 796-802
DOI: 10.1055/s-0041-1739234
Febrasgo Position Statement

Fertility preservation in women with endometriosis

Number 10 - October 2021
Márcia Mendonça Carneiro 
1   Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, MG, Brazil
,
João Sabino Lahorgue da Cunha Filho 
2   Departamento de Ginecologia e Obstetrícia, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil
,
Carlos Alberto Petta 
3   Universidade Estadual de Campinas, Campinas, SP, Brazil. Clínica Fertilidade & Vida, Campinas, SP, Brazil. Serviço de Reprodução Assistida, Hospital Sírio-Libanês, São Paulo, SP, Brazil
,
Carlos Augusto Pires Costa Lino 
4   Hospital Aliança, Salvador, BA, Brazil. Instituto de Perinatologia da Bahia, Salvador, BA, Brazil
,
Corival Lisboa Alves de Castro 
5   Hospital Geral de Goiânia, Goiânia, GO, Brazil
,
Eduardo Schor 
6   Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil. Sociedade Brazileira de Endometriose e Cirurgia Minimamente Invasiva
,
João Nogueira Neto 
7   Universidade Federal do Maranhão, São Luís, MA, Brazil
,
Marco Aurélio Pinho de Oliveira 
8   Faculdade de Ciências Médicas, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, RJ, Brazil
,
Marcos Tcherniakovsky 
9   Setor de Videoendoscopia Ginecológica e Endometriose, Faculdade de Medicina do ABC, Santo André, SP, Brazil
,
Maurício Simões Abrão 
10   Divisão de Ginecologia, Hospital Beneficência Portuguesa de São Paulo, São Paulo, SP, Brazil. Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina, Universidade de São Paulo, São Paulo, SP, Brazil
,
Omero Benedicto Poli Neto 
11   Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil
,
Ricardo de Almeida Quintairos 
12   Núcleo de Endometriose, Hospital Porto Dias, Belém, PA, Brazil
,
Sidney Pearce 
13   Centro Universitário Christus, Fortaleza, CE, Brazil
,
Helizabet Salomão Abdalla 
14   Faculdade de Ciências Médicas, Santa Casa de São Paulo, São Paulo, SP, Brazil
,
Julio Cesar Rosa e Silva 
15   Departamento de Ginecologia e Obstetrícia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, Ribeirão Preto, SP, Brazil
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Key points

  • Endometriosis is a common benign disease that can compromise female fertility.

  • Fertility preservation is a key consideration in the care of girls and women with endometriosis, especially those with ovarian endometriomas.

  • Although there is no definitive study on the subject yet, correct information on disease progression, treatment options, and the risks involved should be available for these women.

  • It is too early to define fertility preservation as the standard of care for all women with endometriosis.

  • Fertility preservation, however, should be considered for women with unoperated bilateral endometriomas and those who have previously removed unilateral endometriomas and need surgery for a contralateral recurrence.

  • Since age is the most important prognostic factor, all patients should be aware of its adverse effect on fertility and pregnancy.

  • Available strategies include cryopreservation of embryos and oocytes.

  • Women should be counseled individually about the risks, benefits and costs involved. In this scenario, the approach of a multidisciplinary team on endometriosis is essential to reach good results.

The National Specialty Commission in Ensometriosis of the Brazilian Federation of Gynecology and Obstetrics Associations (FEBRASGO) endorses to this document. The content production is based on scientific studies on a thematic proposal and the findings presented contribute to clinical practice.




Publication History

Article published online:
16 November 2021

© 2021. Federação Brasileira de Ginecologia e Obstetrícia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. (https://creativecommons.org/licenses/by/4.0/)

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