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DOI: 10.1055/s-0041-1739300
Recurrent Aggressive Osteoblastoma of the Cervical Spine Successfully Treated with Radiotherapy
Article in several languages: português | English
Abstract
Osteoblastoma is a benign disease usually treated with complete resection with curative intent, and it accounts for 14% of the benign bone tumors. A more uncommon presentation refers to a rapid growing mass known as aggressive osteoblastoma. We report the case of a young male with cervical swelling due to a progressive mass on the right side of neck with 3 months of evolution. Incisional biopsy demonstrated grade 3 osteoblastoma. A radical surgical resection was attempted, but complete resection was not feasible because of cervical invasion of C3 without spinal involvement. Despite the lack of robust data, intensity modulated radiotherapy was performed in the ipsilateral cervical region at a dose of 50 Gy in 25 fractions until November 2013. The patient is being followed up regularly without evidence of recurrence since. The so far successful treatment highlights the importance of a multidisciplinary approach for treating patients with aggressive osteoblastoma.
Financial Support
The authors declare that this study received no financial support. All costs for the collection, analysis, interpretation of results, and writing were provided exclusively by the authors.
Work carried out at the Instituto de Oncologia Kaplan, Porto Alegre, RS, Brazil.
Publication History
Received: 25 May 2021
Accepted: 31 August 2021
Article published online:
16 November 2021
© 2021. The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution 4.0 International License, permitting copying and reproduction so long as the original work is given appropriate credit (https://creativecommons.org/licenses/by/4.0/)
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Referências
- 1 Lucas DR, Unni KK, McLeod RA, O'Connor MI, Sim FH. Osteoblastoma: clinicopathologic study of 306 cases. Hum Pathol 1994; 25 (02) 117-134
- 2 Galgano MA, Goulart CR, Iwenofu H, Chin LS, Lavelle W, Mendel E. Osteoblastomas of the spine: a comprehensive review. Neurosurg Focus 2016; 41 (02) E4
- 3 Duarte ML, Prado JLM, Pereira CAM, Alves MTS, Scoppetta LCD. Aggressive osteoblastoma with degeneration to secondary aneurysmal bone cyst. J Bras Patol Med Lab 2019; 55 (04) 426-433
- 4 Pontual ML, Pontual AA, Grempel RG, Campos LR, Costa AdeL, Godoy GP. Aggressive multilocular osteoblastoma in the mandible: a rare and difficult case to diagnose. Braz Dent J 2014; 25 (05) 451-456
- 5 Castro PHS, Molinari DL, Stateri HQ, Borges AH, Volpato LER. Agressive osteoblastoma in a seven-year-old girl's mandible: Treatment and six-year monitoring. Int J Surg Case Rep 2016; 27: 5-9
- 6 Chew FS, Pena CS, Keel SB. Cervical spine osteoblastoma. AJR Am J Roentgenol 1998; 171 (05) 1244
- 7 Janin Y, Epstein JA, Carras R, Khan A. Osteoid osteomas and osteoblastomas of the spine. Neurosurgery 1981; 8 (01) 31-38
- 8 Seki T, Fukuda H, Ishii Y, Hanaoka H, Yatabe S. Malignant transformation of benign osteoblastoma. A case report. J Bone Joint Surg Am 1975; 57 (03) 424-426
- 9 Sim FH, Cupps RE, Dahlin DC, Ivins JC. Postradiation sarcoma of bone. J Bone Joint Surg Am 1972; 54 (07) 1479-1489
- 10 Berberoglu S, Oguz A, Aribal E, Ataoglu O. Osteoblastoma response to radiotherapy and chemotherapy. Med Pediatr Oncol 1997; 28 (04) 305-309