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CC BY-NC-ND 4.0 · Indian J Radiol Imaging 2022; 32(01): 142-144
DOI: 10.1055/s-0041-1739385
Case Report

Calciphylaxis and Ulcerative Lesions of Bilateral Nipple–Areolar Complex Due to Alcoholic Liver Disease

Anamika Jha
1   Department of Radiology, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal
,
Shreya Shrivastav
2   Department of Pathology, Institute of Medicine, Tribhuvan University Teaching Hospital, Maharajgunj, Kathmandu, Nepal
,
Akhilesh K. Kasyap
3   Department of Gastroenterology and Hepatology, Grande International Hospital, Dhapasi, Kathmandu, Nepal
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Abstract

When faced with eczematous lesions involving the nipple–areolar complex (NAC), Paget's disease is assumed to be the diagnosis, anything else being considered a “Zebra” necessitating its exclusion on pathology. A middle-aged lady presented with synchronous asymmetrical ulceration of bilateral NAC with pleomorphic calcifications on mammography and simultaneous extensive vascular calcification in bilateral breasts that suggested systemic cause. Calciphylaxis is a rare diagnosis occurring usually due to underlying end-stage renal disease or hyperparathyroidism. There are very few case reports of calciphylaxis due to alcoholic liver disease and no cases to the best of our knowledge involving NAC. We report an extremely rare case of breast and NAC calciphylaxis due to alcoholic liver disease, highlighting need to consider benign etiology when bilateral involvement is present.

Keywords

breast - calciphylaxis - nipple–areolar complex - Paget's disease

Authors' Contribution

Anamika Jha was involved in conceptualization, definition of intellectual contents, literature search, manuscript preparation, and manuscript editing and review. Shreya Shrivastav was involved in conceptualization, definition of intellectual contents, literature search, and manuscript editing and review. K Akhilesh Kasyap was involved in literature search, manuscript preparation, and manuscript editing and review. Anamika Jha has provided guarantee for this manuscript.




Publication History

Article published online:
01 May 2022

© 2022. Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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