Abstract
Osteoarthritis (OA) is a progressive disease of the synovial joints that causes pain,
functional impairment, disability, and progressive degeneration of the joint. Regarding
its treatments, especially in early stages, there are different interventions to avoid
its development and progression and also to achieve an adequate management of symptoms,
and there are unconventional oral medical treatments with controversial evidence.
The objective of the present paper is to provide an update, to specialists in Orthopedics
and Traumatology, regarding the current evidence on complementary oral therapies in
the treatment of knee osteoarthritis. References are made to the most widely used
and studied complementary pharmacological methods, mentioning the method of action
and the consequences studied on knee osteoarthritis. The article ends with a table
of recommendations based on current evidence.
Keywords
osteoarthritis - pain - knee - chondroitin - diacerein - hyaluronic acid
