Download PDF
CC BY-NC-ND 4.0 · Revista Chilena de Ortopedia y Traumatología 2021; 62(03): e174-e179
DOI: 10.1055/s-0041-1740171
Artículo Original | Original Article

Prevalence of Heterotopic Ossification after Cervical Disk Arthroplasty at 5 Years

Article in several languages: español | English
Ivan A. Stepanov 
1   Departamento de Cirugía General y Anestesiología, Irkutsk State Medical University, Irkutsk, Russia
,
Vladimir A. Beloborodov
1   Departamento de Cirugía General y Anestesiología, Irkutsk State Medical University, Irkutsk, Russia
› Author Affiliations Funding The authors have no sources of funding to declare.
› Further Information
Also available at
   Permissions and Reprints
Zoom Image

Abstract

Introduction In recent years, cervical disk arthroplasty (CDA) has become widely used in patients as a substitute to anterior cervical diskectomy and fusion (ACDF). However, heterotopic ossification (HO) and spontaneous fusion after CDA have been reported, and maintenance of motion following arthroplasty can be hindered by the development of HO.

Materials and Methods The CDA procedure with Activ C and M6-C prostheses was performed on 127 patients. The mean follow-up time was of 58.4 months, ranging from 51 to 66 months.

Results Grade-1 ossifications were present in 11 (8.6%) levels. A total of 45 (35.4%) segments showed grade-2 HO. Cases of HO that led to restrictions in the range of motion were present in 13 (10.2%) patients. Fives year postoperatively, there were only 9 (7.0%) patients with grade-4 ossifications in the M6-C artificial disk prosthesis group. In the survival analysis after HO occurrence, the median survival of the patients was of 28.3 ±  5.6 months. The Activ C artificial disk prosthesis group had a statistically longer survival (49.5 ±  7.8 months) than the M6-C disk group.

Conclusion In the present study, 61.4% of the patients developed HO at a mean follow-up period of 58.4 months. In the survival analysis after HO occurrence, the median survival of the patients was of 28.3 ±  5.6 months. The Activ C artificial disk prosthesis group had a statistically longer survival (49.5 ±  7.8 months) than the M6-C disk group.

Keywords

anterior cervical diskectomy and fusion - cervical disk arthroplasty - heterotopic ossification - prevalence - activ C prosthesis - M6-C prosthesis

Ethical Approval

Institutional review board approval was obtained by the ethics committee at Irkutsk State Medical University (2013–51/5).




Publication History

Received: 03 June 2020

Accepted: 06 August 2021

Article published online:
22 December 2021

© 2021. Sociedad Chilena de Ortopedia y Traumatologia. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commecial purposes, or adapted, remixed, transformed or built upon. (https://creativecommons.org/licenses/by-nc-nd/4.0/)

Thieme Revinter Publicações Ltda.
Rua do Matoso 170, Rio de Janeiro, RJ, CEP 20270-135, Brazil