Abstract
Introduction In recent years, cervical disk arthroplasty (CDA) has become widely used in patients
as a substitute to anterior cervical diskectomy and fusion (ACDF). However, heterotopic
ossification (HO) and spontaneous fusion after CDA have been reported, and maintenance
of motion following arthroplasty can be hindered by the development of HO.
Materials and Methods The CDA procedure with Activ C and M6-C prostheses was performed on 127 patients.
The mean follow-up time was of 58.4 months, ranging from 51 to 66 months.
Results Grade-1 ossifications were present in 11 (8.6%) levels. A total of 45 (35.4%) segments
showed grade-2 HO. Cases of HO that led to restrictions in the range of motion were
present in 13 (10.2%) patients. Fives year postoperatively, there were only 9 (7.0%)
patients with grade-4 ossifications in the M6-C artificial disk prosthesis group.
In the survival analysis after HO occurrence, the median survival of the patients
was of 28.3 ± 5.6 months. The Activ C artificial disk prosthesis group had a statistically
longer survival (49.5 ± 7.8 months) than the M6-C disk group.
Conclusion In the present study, 61.4% of the patients developed HO at a mean follow-up period
of 58.4 months. In the survival analysis after HO occurrence, the median survival
of the patients was of 28.3 ± 5.6 months. The Activ C artificial disk prosthesis
group had a statistically longer survival (49.5 ± 7.8 months) than the M6-C disk
group.
Keywords
anterior cervical diskectomy and fusion - cervical disk arthroplasty - heterotopic
ossification - prevalence - activ C prosthesis - M6-C prosthesis
