Senologie - Zeitschrift für Mammadiagnostik und -therapie 2016; 13(03): 102-105
DOI: 10.1055/s-0042-113577
Aktuell diskutiert
© Georg Thieme Verlag KG Stuttgart · New York

Kongressbericht – ASCO Jahrestagung 2016 – aktuelle Ergebnisse zum Mammakarzinom

A. D. Hartkopf
,
F.-A. Taran
,
S. Y. Brucker
Further Information

Publication History

Publication Date:
05 October 2016 (online)

Auch in diesem Jahr trafen sich mehr als 30 000 Onkologen auf dem Kongress der American Association of Clinical Oncology (ASCO) in Chicago, um die neuesten Ergebnisse aus der onkologischen Grundlagenforschung, translationalen und klinischen Forschung gemeinsam zu diskutieren. Im Folgenden werden die wesentlichen Highlights zum Mammakarzinom vorgestellt.

 
  • Literatur

  • 1 Cortazar P et al. Pathological complete response and long-term clinical benefit in breast cancer: the CTNeoBC pooled analysis. Lancet 2014; 384: 164-172
  • 2 Gianni L et al. Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial. Lancet Oncol 2012; 13: 25-32
  • 3 Schneeweiss A et al. Pertuzumab plus trastuzumab in combination with standard neoadjuvant anthracycline-containing and anthracycline-free chemotherapy regimens in patients with HER2-positive early breast cancer: a randomized phase II cardiac safety study (TRYPHAENA). Ann Oncol 2013; 24: 2278-2284
  • 4 Davies C et al. Long-term effects of continuing adjuvant tamoxifen to 10 years versus stopping at 5 years after diagnosis of oestrogen receptor-positive breast cancer: ATLAS, a randomised trial. Lancet 2013; 381: 805-816
  • 5 Finn RS et al. The cyclin-dependent kinase 4/6 inhibitor palbociclib in combination with letrozole versus letrozole alone as first-line treatment of oestrogen receptor-positive, HER2-negative, advanced breast cancer (PALOMA-1/TRIO-18): a randomised phase 2 study. Lancet Oncol 2015; 16: 25-35
  • 6 Cristofanilli M et al. Fulvestrant plus palbociclib versus fulvestrant plus placebo for treatment of hormone-receptor-positive, HER2-negative metastatic breast cancer that progressed on previous endocrine therapy (PALOMA-3): final analysis of the multicentre, double-blind, phase 3 randomised controlled trial. Lancet Oncol 2016; 17: 425-439
  • 7 Petrelli F, Barni S. Surgery of primary tumors in stage IV breast cancer: an updated meta-analysis of published studies with meta-regression. Med Oncol 2012; 29: 3282-3290
  • 8 Badwe R et al. Locoregional treatment versus no treatment of the primary tumour in metastatic breast cancer: an open-label randomised controlled trial. Lancet Oncol 2015; 16: 1380-1388
  • 9 Soran A et al. Early follow up of a randomized trial evaluating resection of the primary breast tumor in women presenting with de novo stage IV breast cancer; Turkish study (protocol MF07–01). San Antonio Breast Cancer Symposium; 2013 abstr. S2–03