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Exp Clin Endocrinol Diabetes 2017; 125(09): 598-602
DOI: 10.1055/s-0042-114035
Article
© Georg Thieme Verlag KG Stuttgart · New York

Evaluation of Epicardial Adipose Tissue in Patients of Type 2 Diabetes Mellitus by Echocardiography and its Correlation with Intimal Medial Thickness of Carotid Artery

Zihang Wang
1   Department of Diagnostic Ultrasound, Second Affiliated Hospital of Dalian Medical University, Dalian, P. R. China
,
Yuhong Zhang
1   Department of Diagnostic Ultrasound, Second Affiliated Hospital of Dalian Medical University, Dalian, P. R. China
,
Weiwei Liu
2   Library of Dalian Medical University, Dalian, P. R. China
,
Benli Su
3   Department of Endocrinology, Second Affiliated Hospital of Dalian Medical University, Dalian, P. R. China
› Author Affiliations
Further Information

Publication History

received   13 February 2016
first decision 28 July 2016

accepted    29 July 2016

Publication Date:
11 May 2017 (online)

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Abstract

The present study aimed to evaluate the diagnostic value of echocardiography in measuring the thickness of epicardial adipose tissue (EAT) of the patients of type 2 diabetes mellitus (T2DM) and its correlation with the intimal-medial thickness of the carotid artery (cIMT) to investigate the relationship between EAT and cIMT. 68 patients of T2DM were enrolled and were divided into 2 groups: group of T2DM with duration≤10 years (35 cases) and group of T2DM with duration>10 years (33 cases). And 30 healthy subjects were enrolled as the control group. The thickness of EAT and cIMT were measured by echocardiography and high-frequency ultrasonography. The thickness of EAT and IMT of the carotid artery of 2 type 2 diabetic groups (duration≤10 years and>10 years) were significantly higher than that of the control group (all p<0.05), and the thickness of EAT and cIMT of the group of T2DM with duration>10 years were significantly higher than that of the group of T2DM with duration≤10 years (p<0.05). In univariate analysis, the thickness of EAT was positively and significantly associated with age (r=0.412, p<0.05), BMI (r=0.566, p<0.05), waist circumference (r=0.475, p<0.05), LDL (r=0.425, p<0.05), TG (r=0.496, p<0.05), duration of diabetes (r=0.384, p<0.05) and cIMT (r=0.456, p<0.05). In multiple stepwise regression analyses, age, BMI and IMT of carotid artery were appeared to be significantly associated with EAT (p<0.05 for all). In conclusion, routine screening of EAT and cIMT by ultrasonography in type 2 diabetic patients helps us to predict cardiovascular risks and prevent further development of cardiovascular complications.

Key words

epicardial adipose tissue - type 2 diabetes mellitus - intimal-medial thickness - carotid artery - echocardiography
 

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