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Int J Sports Med 2016; 37(13): 1073-1079
DOI: 10.1055/s-0042-114701
Clinical Sciences
© Georg Thieme Verlag KG Stuttgart · New York

Post-Exercise Neurovascular Control in Chronic Heart Failure Patients

T. S. Nobre
1   Heart Institute (InCor), Medical School of University of Sao Paulo, Cardiovascular Rehabilitation and Exercise Physiology Unit, Sao Paulo, Brazil
,
R. V. Groehs
1   Heart Institute (InCor), Medical School of University of Sao Paulo, Cardiovascular Rehabilitation and Exercise Physiology Unit, Sao Paulo, Brazil
,
L. F. Azevedo
1   Heart Institute (InCor), Medical School of University of Sao Paulo, Cardiovascular Rehabilitation and Exercise Physiology Unit, Sao Paulo, Brazil
,
L. M. Antunes-Correa
1   Heart Institute (InCor), Medical School of University of Sao Paulo, Cardiovascular Rehabilitation and Exercise Physiology Unit, Sao Paulo, Brazil
,
D. G. Martinez
2   Unit of Cardiovascular Investigation and Exercise Physiology,Faculty of Physical Education, Federal University of Juiz de Fora, Minas Gerais, Brazil
,
M.J. N. N. Alves
1   Heart Institute (InCor), Medical School of University of Sao Paulo, Cardiovascular Rehabilitation and Exercise Physiology Unit, Sao Paulo, Brazil
,
C.E. Negrao
1   Heart Institute (InCor), Medical School of University of Sao Paulo, Cardiovascular Rehabilitation and Exercise Physiology Unit, Sao Paulo, Brazil
3   School of Physical Education and Sport,University of Sao Paulo - Sao Paulo,Sp, Brazil
› Author Affiliations
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Publication History



accepted after revision 13 July 2016

Publication Date:
27 September 2016 (online)

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Abstract

It remains unknown whether or not a reduction in muscle sympathetic nerve activity in heart failure patients is associated over time with the effects of long- or short-term repeated exercise. 10 chronic heart failure patients, age 49±3 years old, functional class I–III NYHA, ejection fraction <40% were randomly submitted to either an acute bout of moderate continuous exercise OR high-intensity interval exercise. Muscle sympathetic nerve activity (microneurography) and forearm blood flow (venous occlusion plethysmography) were evaluated pre- and post-exercise sessions. The moderate exercise consisted of cycle exercise at an intensity corresponding to anaerobic threshold. The interval exercise consisted of a 2-min cycle exercise at intensity corresponding to anaerobic threshold, followed by a 1-min exercise set at respiratory compensation point. Exercise capacity was evaluated by cardiopulmonary exercise test. The caloric expenditure in both sessions was 100 kcal. Baseline muscle sympathetic nerve activity and forearm blood flow levels were not different between sessions. Moderate or high-intensity exercise caused no significant changes in muscle sympathetic nerve activity and forearm blood flow. These findings suggest that the reduction in muscle sympathetic nerve activity and the increase in forearm blood flow provoked by exercise training in chronic heart failure patients are due to cumulative effects over time.

Key word

sympathetic nerve activity - muscle blood flow - acute exercise
 

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