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Geburtshilfe Frauenheilkd 2016; 76(11): 1126-1131
DOI: 10.1055/s-0042-117696
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Georg Thieme Verlag KG Stuttgart · New York

Gynäkologische Tumoren – Therapie und Prognosefaktoren uteriner Sarkome – Was ist neu?

Mareike Sporkmann
,
Florian Heitz
,
Philipp Harter
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Publication Date:
25 November 2016 (online)

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Die uterinen Sarkome sind eine inhomogene Gruppe seltener, meist aggressiver Tumoren der Uterusmuskulatur, des endometrialen Stromas oder des uterinen Bindegewebes. Sie setzt sich aus histologisch verschiedenen Subtypen zusammen: zu den Sarkomen mesenchymalen Ursprungs gehören das Leiomyosarkom (LMS), low-grade und high-grade endometriale Stromasarkome (ESS) sowie das undifferenzierte Stromasarkom. Sarkome mit gemischt epithelial-mesenchymalem Ursprung sind das Adenosarkom und das Karzinosarkom. Die Inzidenz liegt bei 0,5–3,3 / 100 000 Frauen / Jahr [1] . Auf Grund der histologischen Diversität sind die empfohlenen Therapieansätze für jede Subgruppe spezifisch und werden im Folgenden einzeln beleuchtet.

 

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